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<!---#### $Id: meme-intro.html 1339 2006-09-21 19:46:28Z tbailey $#### $Log$## Revision 1.2 2006/03/07 23:30:20 nadya## merge branches v3_5_1 and v3_5_2 back to the trunk#### Revision 1.1.1.1.6.1 2006/02/22 20:49:02 nadya## enabling styling with js and css#### Revision 1.1.1.1 2005/07/31 20:18:03 nadya## Importing from meme-3.0.14, and adding configure/make####---><HTML><HEAD><TITLE> MEME - Overview</TITLE><script src="template-css.js" type="text/javascript"></script></HEAD><body class="body"><script src="template-header.js" type="text/javascript"></script><H1>MEME -- Multiple EM for Motif Elicitation </H1><H2><I>Motif discovery tool</I></H2><HR><H3> Overview </H3><H4> MEME is a tool for discovering <B>motifs</B> in a group of related DNA or protein sequences.<P> A motif is a sequence pattern that occurs repeatedly in a group of related protein or DNA sequences. MEME represents motifs as position-dependent letter-probability matrices which describe the probability of each possible letter at each position in the pattern. Individual MEME motifs do not contain gaps. Patterns with variable-length gaps are split by MEME into two or more separate motifs.<P> MEME takes as <A HREF=meme-input.html>input</A> a group of DNA or protein sequences (the <I>training set</I>) and outputs as many motifs as requested. MEME uses statistical modeling techniques to automatically choose the best width, number of occurrences, and description for each motif. <P> MEME sends you three e-mail messages:<UL> <LI> <B>a confirmation message</B>, <LI> the <A HREF="meme-output-example.html#explanation"><B>MEME results</B></A>, and <LI> the <A HREF=mast-intro.html><B>MAST results</B></A> of searching the training set for the motifs found by MEME using <A HREF=mast-intro.html><B>MAST</B></A>.</UL><P></H4><HR><H3><A HREF="meme.html">Discover</A> motifs using MEME.</H3> <HR><font>Return to <A href="intro.html"><B>MEME SYSTEM introduction</B></A>.</font><HR><script src="template-footer.js" type="text/javascript"></script></BODY></HTML>
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