mast.adh.oops

EM算法的改进

GUTD_ECOLI
  SORBITOL-6-PHOSPHATE 2-DEHYDROGENASE (EC 1.1.1.140) (GLUCITOL-6- PHOSPHATE 
  DEHYDROGENASE) (KETOSEPHOSPHATE REDUCTASE)
  LENGTH = 259  COMBINED P-VALUE = 1.54e-26  E-VALUE =  5.1e-25
  DIAGRAM: 2_[2]_122_[1]_77

       [2]
       1.5e-14
       KVVLITGCSSGIGKATAKHLHKEGAKVVL
       +++++ ++++ ++  +++ ++++++++ +
1    MNQVAVVIGGGQTLGAFLCHGLAAEGYRVAVVDIQSDKAANVAQEINAEYGESMAYGFGADATSEQSCLALSRGV

        [1]
        3.0e-19
        YSASKFAVRMLTRSMAHEYAPHGIRVNCI
        +++++++ +++++++++++++++++++++
151  NSGYSAAKFGGVGLTQSLALDLAEYGITVHSLMLGNLLKSPMFQSLLPQYATKLGIKPDQVEQYYIDKVPLKRGC


DHB3_HUMAN
  no comment
  LENGTH = 310  COMBINED P-VALUE = 2.53e-26  E-VALUE =  8.3e-25
  DIAGRAM: 48_[2]_120_[1]_84

                                                     [2]
                                                     7.4e-19
                                                     KVVLITGCSSGIGKATAKHLHKEGAKV
                                                     +++++++++ ++++++  ++++++ ++
1    MGDVLEQFFILTGLLVCLACLAKCVRFSRCVLLNYYKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNV

     
     
     VL
     ++
76   VLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLNAPDEI

                                                    [1]
                                                    6.7e-15
                                                    YSASKFAVRMLTRSMAHEYAPHGIRVNC
                                                    ++++++++++++++++ +++ + + +++
151  QSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQV

     
     
     I
     +
226  LTPYAVSTAMTKYLNTNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAFQRLLLTHYV


3BHD_COMTE
  3-BETA-HYDROXYSTEROID DEHYDROGENASE (EC 1.1.1.51)
  LENGTH = 253  COMBINED P-VALUE = 4.25e-26  E-VALUE =  1.4e-24
  DIAGRAM: 6_[2]_115_[1]_74

           [2]
           2.6e-18
           KVVLITGCSSGIGKATAKHLHKEGAKVVL
           +++++++++++ ++++++ ++ +++++
1    TNRLQGKVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGERSMFVRHDVSSEADWTLVMAAVQ

     [1]
     5.1e-15
     YSASKFAVRMLTRSMAHEYAPHGIRVNCI
     +++++++++++++++++ +++++  +++
151  YSASKAAVSALTRAAALSCRKQGYAIRVNSIHPDGIYTPMMQASLPKGVSKEMVLHDPKLNRAGRAYMPERIAQL


LIGD_PSEPA
  C ALPHA-DEHYDROGENASE (EC -.-.-.-)
  LENGTH = 305  COMBINED P-VALUE = 2.45e-25  E-VALUE =  8.1e-24
  DIAGRAM: 6_[2]_121_[1]_120

           [2]
           6.5e-17
           KVVLITGCSSGIGKATAKHLHKEGAKVVL
           +++ +++++++ ++  ++ + ++++++++
1    MKDFQDQVAFITGGASGAGFGQAKVFGQAGAKIVVADVRAEAVEKAVAELEGLGITAHGIVLDIMDREAYARAAD

           [1]
           7.9e-16
           YSASKFAVRMLTRSMAHEYAPHGIRVNCI
           +++++++ +++++ +++ ++++++ ++++
151  SALAGPYSAAKAASINLMEGYRQGLEKYGIGVSVCTPANIKSNIAEASRLRPAKYGTSGYVENEESIASLHSIHQ


DHES_HUMAN
  ESTRADIOL 17 BETA-DEHYDROGENASE (EC 1.1.1.62) (20 ALPHA-HYDROXYSTEROID 
  DEHYDROGENASE) (E2DH) (17-BETA-HSD) (PLACENTAL 17-BETA-HYDROXYSTEROID 
  DEHYDROGENASE)
  LENGTH = 327  COMBINED P-VALUE = 7.31e-24  E-VALUE =  2.4e-22
  DIAGRAM: 2_[2]_50_[2]_44_[1]_144

       [2]
       1.4e-14
       KVVLITGCSSGIGKATAKHLHKEGAKVVL
       +++++++++++++++++ +++++ ++ +
1    ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAA

           [2]
           9.3e-05
           KVVLITGCSSGIGKATAKHLHKEGAKVVL
            ++ +  ++ ++++   ++ + + +   +
76   RERVTEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLP

         [1]
         1.0e-16
         YSASKFAVRMLTRSMAHEYAPHGIRVNCI
         +++++++++++++++++ + + +++ + +
151  FNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQV


RFBB_NEIGO
  no comment
  LENGTH = 346  COMBINED P-VALUE = 9.68e-21  E-VALUE =  3.2e-19
  DIAGRAM: 6_[2]_129_[1]_153

           [2]
           1.8e-13
           KVVLITGCSSGIGKATAKHLHKEGAKVVL
           ++++++++++ ++ +++++ +++    ++
1    MQTEGKKNILVTGGAGFIGSAVVRHIIQNTRDSVVNLDKLTYAGNLESLTDIADNPRYAFEQVDICDRAELDRVF

                   [1]
                   1.0e-14
                   YSASKFAVRMLTRSMAHEYAPHGIRVNCI
                   +++++++ +++++++++ ++   ++ ++
151  DLFTETTPYAPSSPYSASKAAADHLVRAWQRTYRLPSIVSNCSNNYGPRQFPEKLIPLMILNALSGKPLPVYGDG


BPHB_PSEPS
  BIPHENYL-CIS-DIOL DEHYDROGENASE (EC 1.3.1.-)
  LENGTH = 275  COMBINED P-VALUE = 3.02e-20  E-VALUE =    1e-18
  DIAGRAM: 5_[2]_118_[1]_94

          [2]
          8.6e-15
          KVVLITGCSSGIGKATAKHLHKEGAKVVL
            +++++++++++++++ +++++    ++
1    MKLKGEAVLITGGASGLGRALVDRFVAEAKVAVLDKSAERLAELETDLGDNVLGIVGDVRSLEDQKQAASRCVAR

       [1]
       1.2e-12
       YSASKFAVRMLTRSMAHEYAPHGIRVNCI
       ++++++++++++++++++++++  +  +
151  PLYTAAKQAIVGLVRELAFELAPYVRVNGVGPGGMNSDMRGPSSLGMGSKAISTVPLADMLKSVLPIGRMPEVEE


YURA_MYXXA
  no comment
  LENGTH = 258  COMBINED P-VALUE = 5.64e-20  E-VALUE =  1.9e-18
  DIAGRAM: 65_[2]_22_[2]_14_[1]_70

                                                                      [2]
                                                                      5.6e-05
                                                                      KVVLITGCSS
                                                                        + ++ ++
1    RQHTGGLHGGDELPDGVGDGCLQRPGTRAGAVARQAGVRVFAAGRRLPQLQAADEAPGGRRHRGARGVDVTKADA

                                              [2]
                                              5.7e-08
     GIGKATAKHLHKEGAKVVL                      KVVLITGCSSGIGKATAKHLHKEGAKVVL
      + +  +++  + +   ++                        + +++++  +   + ++  ++  + +
76   TLERIRALDAEAGGLDLVVANAGVGGTTNAKRLPWERVRGIIDTNVTGAAATLSAVLPQMVERKRGHLVGVSSLA

              [1]
              3.8e-19
              YSASKFAVRMLTRSMAHEYAPHGIRVNCI
              +++++++++ ++++++++++ ++++++++
151  GFRGLPATRYSASKAFLSTFMESLRVDLRGTGVRVTCIYPGFVKSELTATNNFPMPFLMETHDAVELMGKGIVRG


PCR_PEA
  no comment
  LENGTH = 399  COMBINED P-VALUE = 2.17e-19  E-VALUE =  7.2e-18
  DIAGRAM: 25_[1]_32_[2]_284

                              [1]
                              1.7e-08
                              YSASKFAVRMLTRSMAHEYAPHGIRVNCI
                                ++ ++++++++++  +   +  +++ +
1    MALQTASMLPASFSIPKEGKIGASLKDSTLFGVSSLSDSLKGDFTSSALRCKELRQKVGAVRAETAAPATPAVNK

                [2]
                1.9e-18
                KVVLITGCSSGIGKATAKHLHKEGAKVVL
                 +++++++++++++++++++++++ + ++
76   SSSEGKKTLRKGNVVITGASSGLGLATAKALAESGKWHVIMACRDYLKAARAAKSAGLAKENYTIMHLDLASLDS


DHCA_HUMAN
  no comment
  LENGTH = 276  COMBINED P-VALUE = 3.43e-19  E-VALUE =  1.1e-17
  DIAGRAM: 4_[2]_159_[1]_55

         [2]
         4.0e-16
         KVVLITGCSSGIGKATAKHLHKEGAKVVL
         ++++++++++++++++++++++  +  ++
1    SSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDF

                                               [1]
                                               2.9e-10
                                               YSASKFAVRMLTRSMAHEYAPHGIRVNCI
                                               ++ ++ +++ +++ +++ +++++   +++
151  PELQQKFRSETITEEELVGLMNKFVEDTKKGVHQKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNAC


ADH_DROME
  ALCOHOL DEHYDROGENASE (EC 1.1.1.1)
  LENGTH = 255  COMBINED P-VALUE = 8.17e-16  E-VALUE =  2.7e-14
  DIAGRAM: 6_[2]_116_[1]_75

           [2]
           1.1e-10
           KVVLITGCSSGIGKATAKHLHKEGAKVVL
           ++++   + +++++ + ++++++  +  +
1    SFTLTNKNVIFVAGLGGIGLDTSKELLKRDLKNLVILDRIENPAAIAELKAINPKVTVTFYPYDVTVPIAETTKL

      [1]
      3.6e-12
      YSASKFAVRMLTRSMAHEYAPHGIRVNCI
      ++ ++++++++++++++    ++++ +++
151  VYSGTKAAVVNFTSSLAKLAPITGVTAYTVNPGITRTTLVHKFNSWLDVEPQVAEKLLAHPTQPSLACAENFVKA


MAS1_AGRRA
  no comment
  LENGTH = 476  COMBINED P-VALUE = 9.22e-16  E-VALUE =    3e-14
  DIAGRAM: 245_[2]_74_[1]_14_[1]_56


                         [2]
                         2.9e-15
                         KVVLITGCSSGIGKATAKHLHKEGAKVVL
                         +++++ + +++ ++++++++++++++  +
226  GRVLHFRRGFSHWTVEIHQSPVILVSGSNRGVGKAIAEDLIAHGYRLSLGARKVKDLEVAFGPQDEWLHYARFDA

                                                     [1]
                                                     4.0e-08
                                                     YSASKFAVRMLTRSMAHEYAPHGIRVN
                                                     +  + + +++   ++ + +++   +++
301  EDHGTMAAWVTAAVEKFGRIDGLVNNAGYGEPVNLDKHVDYQRFHLQWYINCVAPLRMTELCLPHLYETGSGRIV

                     [1]
                     8.7e-05
     CI              YSASKFAVRMLTRSMAHEYAPHGIRVNCI
     ++              + +++ ++ +++++ ++     +     +
376  NINSMSGQRVLNPLVGYNMTKHALGGLTKTTQHVGWDRRCAAIDICLGFVATDMSAWTDLIASKDMIQPEDIAKL


FABI_ECOLI
  no comment
  LENGTH = 262  COMBINED P-VALUE = 2.94e-15  E-VALUE =  9.7e-14
  DIAGRAM: 6_[2]_123_[1]_75

           [2]
           4.5e-10
           KVVLITGCSSGIGKATAKHLHKEGAKVVL
           +++++++ ++ +  ++ ++ +++     +
1    MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMF

             [1]
             3.1e-12
             YSASKFAVRMLTRSMAHEYAPHGIRVNCI
             ++ +++++++ +++++  +++++++++++
151  RAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDV


CSGA_MYXXA
  no comment
  LENGTH = 166  COMBINED P-VALUE = 7.50e-14  E-VALUE =  2.5e-12
  DIAGRAM: 51_[2]_7_[1]_50

                                                        [2]
                                                        9.0e-08
                                                        KVVLITGCSSGIGKATAKHLHKEG
                                                        + ++  +  ++  + +++   +++
1    MRAFATNVCTGPVDVLINNAGVSGLWCALGDVDYADMARTFTINALGPLRVTSAMLPGLRQGALRRVAHVTSRMG

                 [1]
                 1.3e-12
     AKVVL       YSASKFAVRMLTRSMAHEYAPHGIRVNCI
     +           + ++++++ + ++++  ++++++ + + +
76   SLAANTDGGAYAYRMSKAALNMAVRSMSTDLRPEGFVTVLLHPGWVQTDMGGPDATLPAPDSVRGMLRVIDGLNP

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CPU: rocks-155.sdsc.edu
Time 0.025996 secs.

mast meme.adh.oops