📄 optd1.m
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function [Ab] = optd1(ts,N,Nc,beta,gen)
% function [M] = optd1(ts,N,Nc,beta,gen)
% M -> matrix of memory cells
% ts -> suppression threshold
% N -> clone number multiplier
% Nc -> no. of clones to be generated
% beta -> decay of the inverse exponential function
% gen -> maximum number of generations
%
% Function to be Optimized
clc;
ts = 0.1; N = 20; Nc = 10; beta = 100;gen = 2000;
f='exp(-2.0*log(2).*(x-0.1).^2/0.64).*(sin(5.*pi*x).^6)';
%f='(sin(5*pi*(x.^0.75-0.05))).^6';
% Parameters for Ploting the Affinity Landscape
xmin = 0; xmax = 1; x=xmin:0.001:xmax;
vxp = x;
vyp = eval(f);
% Initial Random Population Within the Intervals (xmin/xmax; ymin/ymax)
Ab = xmin + rand(N,1).*(xmax - xmin);
x = Ab;
fit = eval(f);
figure(1);
imprime(f,1,vxp,vyp,x,fit,1,1);title('Initial Population');
% CHECK POSSIBILITY OF USING THE MST TO DETERMINE THE NUMBER OF OPTIMUM ...
it = 0; Nold = N + 1; Nsup = N;
FLAG = 0; FLAGERROR = 0;
avfitold = mean(fit); avfit = avfitold-1;
vout = []; vavfit = []; vN = [];
% Main Loop
while it < gen & FLAG == 0,
% Reproduction (Cloning), Affinity Maturation, and Selection Within Each Clone
[Ab] = clone_mut_select(Ab,Nc,beta,norma(fit),xmin,xmax,f);
% Immune Network Interactions After a Number of Iterations
if rem(it,5) == 0,
if abs(1-avfitold/avfit) < .001,
[Ab] = suppress(Ab,ts);
FLAGERROR = 1;
Nsupold = Nsup; Nsup = size(Ab,1); vN = [vN,Nsup];
% Convergence Criterion
if (Nsupold-Nsup) == 0, % & rem(it,20) == 0,
FLAG = 1; FLAGERROR = 0;
end;
end;
end;
% Insert randomly generated individuals
if FLAGERROR == 1,
d = round(.4*N);
Ab1 = xmin + rand(d,1).*(xmax - xmin);
Ab=[Ab;Ab1];
FLAGERROR = 0;
end;
% Evaluating Fitness
x = Ab;
fit = eval(f); avfitold = avfit;
[out,I] = max(fit); avfit = mean(fit);
% Ploting Results
imprime(f,1,vxp,vyp,x,fit,it,10);
N = size(Ab,1);
it = it + 1; vout = [vout,out]; vavfit = [vavfit,avfit]; % vN = [vN,N];
disp(sprintf('It: %d Max: %f Av: %f Net size: %d',it,out,avfit,N));
end;
imprime2(f,1,vxp,vyp,x,fit,1,1);
figure(2); plot(vout); hold on; plot(vavfit,'-.'); title('Fitness'); hold off;
figure(3); plot(vN); title('N');
disp(sprintf('找到以下%d个极值点:',N));
ymax=-1000;imax=-1;xmax=-1000;
for i=1:N,
x = Ab(i);
y = eval(f);
if y>ymax,
imax=i;xmax=x;ymax=y;
end;
disp(sprintf('f(%f)=%f',x,y));
end;
disp(sprintf('其中,最大值f(%f)=%f',xmax,ymax));
% ------------------- %
% SECONDARY FUNCTIONS %
% ------------------- %
function [C] = clone_mut_select(Ab,Nc,beta,fitin,xmin,xmax,f);
% C -> matrix of clones
% g -> vector with Gaussian mutation
% Ab -> matrix of antibodies
% N -> cardinality of Ab
% Nc -> number of clones for each candidate
[N,L] = size(Ab);
C = [];
for i=1:N,
vones = ones(Nc,1);
Cc = vones * Ab(i,:);
g = (randn(Nc,L)./beta) .* exp(-fitin(i));
g(1,:) = zeros(1,L); % Keep one previous individual for each clone unmutated
c = Cc + g;
% Keeps all elements of the population within the allowed bounds
Ixmin = find(c(:,1) < xmin); Ixmax = find(c(:,1) > xmax);
% Iymin = find(c(:,2) < ymin); Iymax = find(c(:,2) > ymax);
if ~isempty(Ixmin),
c(Ixmin,1) = Cc(length(Ixmin),1);
end;
if ~isempty(Ixmax),
c(Ixmax,1) = Cc(length(Ixmax),1);
end;
x=c;
fit = eval(f);
[out,I] = max(fit);
C = [C;c(I,:)]; % C contains only the best individuals of each clone
end;
% Function suppress self-recognizing and non-stimulated Ab from Memory (M)
function [M] = suppress(M,ts);
% M -> memory matrix
% D1 -> idiotypic affinity matrix
D1 = dist(M,M');
aux = triu(D1,1);
[Is,Js] = find(aux>0 & aux<ts);
if ~isempty(Is),
Is = ver_eq(Is);
M = extract(M,Is);
% D1 = extract(D1,Is);
end;
% Search for repeated indexes
function [Is] = ver_eq(I);
l = length(I); Is = [];
if l > 1,
for i=1:l-1,
aux = I(i);
auxI = I(i+1:end);
el = find(auxI == aux);
if isempty(el),
Is = [Is,aux];
end;
end;
Is = [Is,I(end)];
else,
Is = I;
end;
% Function Extracts lines from M indexed by I
function [M] = extract(M,I);
Maux = zeros(size(M));
Maux(I,:) = M(I,:);
M = M - Maux;
[I] = find(M(:,1)~=0);
M = M(I,:);
% Function normalizes matrix over [0,1]
function [Dn] = norma(D);
% Dn -> normalized vector over [0,1]
[np,ni] = size(D);
if ni == 1,
Dn = (D - min(D))./(max(D)-min(D));
else,
vmaxD = max(D); vminD = min(D);
for i=1:ni,
Dn(:,i) = (D(:,i) - vminD(i))./(vmaxD(i)-vminD(i));
end;
end;
% End Function NORMA
% Print Affinity Landscape and Population of Individuals
function [] = imprime(f,PRINT,vx,vy,x,fx,it,mit);
% x,fx -> current values
% vxplot, vplot -> original (base) function
if PRINT == 1,
if rem(it,mit) == 0,
hold on;
fplot(f,[0 1 0 1],'k-')
xlabel('x'); ylabel('f(x)');
plot(x,fx,'k*'); drawnow; hold off; % pause
end;
end;
function [] = imprime2(f,PRINT,vx,vy,x,fx,it,mit);
% x,fx -> current values
% vxplot, vplot -> original (base) function
if PRINT == 1,
if rem(it,mit) == 0,
hold on;
fplot(f,[0 1 0 1],'k-')
xlabel('x'); ylabel('f(x)');
plot(x,fx,'ro'); drawnow; hold off; % pause
end;
end;
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