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<HTML><HEAD>    <TITLE>Integrated Microscopy Resource</TITLE></HEAD><BODY BACKGROUND="/mbinfo/GIF/mbbg.GIF"><P><CENTER><!WA0><!WA0><!WA0><!WA0><!WA0><!WA0><!WA0><!WA0><!WA0><IMG SRC="http://www.bocklabs.wisc.edu/imr/GIF/imrlogo.GIF" WIDTH="482" HEIGHT="146" NATURALSIZEFLAG="3" ALIGN=bottom></CENTER><CENTER><H2>Integrated Microscopy Resource (IMR)</H2></CENTER><CENTER><H3>An NIH Biomedical Research Technology Resource</H3></CENTER><HR SIZE="6">Director: <!WA1><!WA1><!WA1><!WA1><!WA1><!WA1><!WA1><!WA1><!WA1><A HREF="http://www.bocklabs.wisc.edu/imr/staffprofiles/imrstaff.html#jwhite">John G.White </A>Deputy Director: <!WA2><!WA2><!WA2><!WA2><!WA2><!WA2><!WA2><!WA2><!WA2><A HREF="http://www.bocklabs.wisc.edu/imr/staffprofiles/imrstaff.html#vfrohlich">Victoria Centonze Frohlich </A>Co-investigator: Hans Ris<BR><HR>The Integrated Microscopy Resource (IMR) is a national resource fundedby the Biological Research Technologies Program of the National Institutesof Health (NIH). The resource provides innovative instrumentation and skilledpersonnel to enable investigators to observe their specimens using powerful,new light and electron microscopy techniques. Optical sectioning light microscopycan provide 3-D dynamic (4-D) information on live specimens while rapidcryo preservation techniques allow ultrastructural characterization at adefined timepoint. Topographic and ultrastructural information can be obtainedby field-emission scanning electron microscopy (FESEM) and transmissionelectron microscopy (TEM) respectively. The integrating of LM, FESEM andTEM is capable of providing the combination of structural and functionalinformation. The IMR has an active instrumentation development program thatis aimed at developing improved methods of optical sectioning microscopyfor <I>in vivo</I> imaging. In addition, specimen preparation techniquesare being developed that allow samples to be preserved with a high degreeof structural fidelity for FESEM and TEM.<HR> <!WA3><!WA3><!WA3><!WA3><!WA3><!WA3><!WA3><!WA3><!WA3><A HREF = "http://www.mckinley.com/"><!WA4><!WA4><!WA4><!WA4><!WA4><!WA4><!WA4><!WA4><!WA4><IMG SRC="http://www.bocklabs.wisc.edu/imr/GIF/4star44pix.gif" ALIGN = LEFT></A><BR>The Integrated Microscopy Resource Web site has been selected by<BR>The McKinley Group's professional editorial team as a "4-Star" site.<P><BR><BR><HR SIZE=2 WIDTH=100%><!WA5><!WA5><!WA5><!WA5><!WA5><!WA5><!WA5><!WA5><!WA5><A HREF="http://www.bocklabs.wisc.edu/imr/geninfo3.html"><!WA6><!WA6><!WA6><!WA6><!WA6><!WA6><!WA6><!WA6><!WA6><IMG SRC="http://www.bocklabs.wisc.edu/imr/icons/ball-red.gif" WIDTH="14" HEIGHT="14" NATURALSIZEFLAG="3" ALIGN=bottom>Symposium and Short Course on Applications of Multi-Photon Excitation Imaging <BR> August 9-August 11, 1997 - Cleveland, Ohio</A><BR><!WA7><!WA7><!WA7><!WA7><!WA7><!WA7><!WA7><!WA7><!WA7><A HREF="http://www.bocklabs.wisc.edu/imr/geninfo2.html"><!WA8><!WA8><!WA8><!WA8><!WA8><!WA8><!WA8><!WA8><!WA8><IMG SRC="http://www.bocklabs.wisc.edu/imr/icons/ball-red.gif" WIDTH="14" HEIGHT="14" NATURALSIZEFLAG="3" ALIGN=bottom>Second Annual Symposium on IntegratedMicroscopy - Sept 20th-Sept 22nd 1996</A><BR><!WA9><!WA9><!WA9><!WA9><!WA9><!WA9><!WA9><!WA9><!WA9><A HREF="http://www.bocklabs.wisc.edu/imr/geninfo.html"><!WA10><!WA10><!WA10><!WA10><!WA10><!WA10><!WA10><!WA10><!WA10><IMG SRC="http://www.bocklabs.wisc.edu/imr/icons/ball-red.gif" WIDTH="14" HEIGHT="14" NATURALSIZEFLAG="3" ALIGN=bottom>First Annual Symposium on IntegratedMicroscopy - Sept 29th-Oct 1st 1995</A> <HR><CENTER><H3>Instruments and Facilities</H3></CENTER><!WA11><!WA11><!WA11><!WA11><!WA11><!WA11><!WA11><!WA11><!WA11><A HREF="http://www.bocklabs.wisc.edu/imr/instruments/2ptrapping.html"><!WA12><!WA12><!WA12><!WA12><!WA12><!WA12><!WA12><!WA12><!WA12><IMG SRC="http://www.bocklabs.wisc.edu/imr/icons/ball-red.gif" WIDTH="14" HEIGHT="14" NATURALSIZEFLAG="3" ALIGN=bottom></A><!WA13><!WA13><!WA13><!WA13><!WA13><!WA13><!WA13><!WA13><!WA13><A HREF="http://www.bocklabs.wisc.edu/imr/instruments/2ptrapping.html">Opticaltrapping</A><BR><!WA14><!WA14><!WA14><!WA14><!WA14><!WA14><!WA14><!WA14><!WA14><A HREF="http://www.bocklabs.wisc.edu/imr/instruments/confocal.html"><!WA15><!WA15><!WA15><!WA15><!WA15><!WA15><!WA15><!WA15><!WA15><IMG SRC="http://www.bocklabs.wisc.edu/imr/icons/ball-red.gif" WIDTH="14" HEIGHT="14" NATURALSIZEFLAG="3" ALIGN=bottom>Confocal imaging system</A><BR><!WA16><!WA16><!WA16><!WA16><!WA16><!WA16><!WA16><!WA16><!WA16><A HREF="http://www.bocklabs.wisc.edu/imr/instruments/4D/4d.html"><!WA17><!WA17><!WA17><!WA17><!WA17><!WA17><!WA17><!WA17><!WA17><IMG SRC="http://www.bocklabs.wisc.edu/imr/icons/ball-red.gif" WIDTH="14"HEIGHT="14" NATURALSIZEFLAG="3" ALIGN=bottom>Four-dimensional image archivalsystem</A><BR><!WA18><!WA18><!WA18><!WA18><!WA18><!WA18><!WA18><!WA18><!WA18><A HREF="http://www.bocklabs.wisc.edu/imr/instruments/2p.html"><!WA19><!WA19><!WA19><!WA19><!WA19><!WA19><!WA19><!WA19><!WA19><IMG SRC="http://www.bocklabs.wisc.edu/imr/icons/ball-red.gif" WIDTH="14" HEIGHT="14" NATURALSIZEFLAG="3" ALIGN=bottom>Multi-photon imaging systemfor in vivo fluorescence microscopy</A><BR><!WA20><!WA20><!WA20><!WA20><!WA20><!WA20><!WA20><!WA20><!WA20><A HREF="http://www.bocklabs.wisc.edu/imr/instruments/spfem.html"><!WA21><!WA21><!WA21><!WA21><!WA21><!WA21><!WA21><!WA21><!WA21><IMG SRC="http://www.bocklabs.wisc.edu/imr/icons/ball-red.gif" WIDTH="14"HEIGHT="14" NATURALSIZEFLAG="3" ALIGN=bottom>Rapid cryo immobilization /specimen preparation</A><BR><!WA22><!WA22><!WA22><!WA22><!WA22><!WA22><!WA22><!WA22><!WA22><A HREF="http://www.bocklabs.wisc.edu/imr/instruments/sem/fesem.html"><!WA23><!WA23><!WA23><!WA23><!WA23><!WA23><!WA23><!WA23><!WA23><IMG SRC="http://www.bocklabs.wisc.edu/imr/icons/ball-red.gif" WIDTH="14" HEIGHT="14" NATURALSIZEFLAG="3" ALIGN=bottom>Field-emission scanningelectron microscope (FESEM)</A><BR><!WA24><!WA24><!WA24><!WA24><!WA24><!WA24><!WA24><!WA24><!WA24><A HREF="http://www.bocklabs.wisc.edu/imr/instruments/hvem.html"><!WA25><!WA25><!WA25><!WA25><!WA25><!WA25><!WA25><!WA25><!WA25><IMG SRC="http://www.bocklabs.wisc.edu/imr/icons/ball-red.gif" WIDTH="14"HEIGHT="14" NATURALSIZEFLAG="3" ALIGN=bottom>TEM at the IMR</A><BR><HR><H3 ALIGN=CENTER>Other IMR Information</H3><!WA26><!WA26><!WA26><!WA26><!WA26><!WA26><!WA26><!WA26><!WA26><A HREF="http://www.bocklabs.wisc.edu/imr/imrpub.html"><!WA27><!WA27><!WA27><!WA27><!WA27><!WA27><!WA27><!WA27><!WA27><IMG SRC="http://www.bocklabs.wisc.edu/imr/icons/ball-red.gif"></A><!WA28><!WA28><!WA28><!WA28><!WA28><!WA28><!WA28><!WA28><!WA28><A HREF="http://www.bocklabs.wisc.edu/imr/imrpub.html">Selected Publications from the IMR</A><BR><!WA29><!WA29><!WA29><!WA29><!WA29><!WA29><!WA29><!WA29><!WA29><A HREF="http://www.bocklabs.wisc.edu/imr/imrinfo.html"><!WA30><!WA30><!WA30><!WA30><!WA30><!WA30><!WA30><!WA30><!WA30><IMG SRC="http://www.bocklabs.wisc.edu/imr/icons/ball-red.gif"></A><!WA31><!WA31><!WA31><!WA31><!WA31><!WA31><!WA31><!WA31><!WA31><A HREF="http://www.bocklabs.wisc.edu/imr/imrinfo.html">IMR History, Mission and Research Activities</A><BR><!WA32><!WA32><!WA32><!WA32><!WA32><!WA32><!WA32><!WA32><!WA32><A HREF="http://www.bocklabs.wisc.edu/imr/staffprofiles/imrstaff.html"><!WA33><!WA33><!WA33><!WA33><!WA33><!WA33><!WA33><!WA33><!WA33><IMG SRC="http://www.bocklabs.wisc.edu/imr/icons/ball-red.gif"></A> <!WA34><!WA34><!WA34><!WA34><!WA34><!WA34><!WA34><!WA34><!WA34><A HREF="http://www.bocklabs.wisc.edu/imr/staffprofiles/imrstaff.html">IMR Staff</A><BR><!WA35><!WA35><!WA35><!WA35><!WA35><!WA35><!WA35><!WA35><!WA35><A HREF="http://www.bocklabs.wisc.edu/imr/app.html"><!WA36><!WA36><!WA36><!WA36><!WA36><!WA36><!WA36><!WA36><!WA36><IMG SRC="http://www.bocklabs.wisc.edu/imr/icons/ball-red.gif"></A> <!WA37><!WA37><!WA37><!WA37><!WA37><!WA37><!WA37><!WA37><!WA37><A HREF="http://www.bocklabs.wisc.edu/imr/app.html">Application Procedures</A><BR><!WA38><!WA38><!WA38><!WA38><!WA38><!WA38><!WA38><!WA38><!WA38><A HREF="http://www.bocklabs.wisc.edu/imr/statistics/imrstats.html"><!WA39><!WA39><!WA39><!WA39><!WA39><!WA39><!WA39><!WA39><!WA39><IMG SRC="http://www.bocklabs.wisc.edu/imr/icons/ball-red.gif"></A> <!WA40><!WA40><!WA40><!WA40><!WA40><!WA40><!WA40><!WA40><!WA40><A HREF="http://www.bocklabs.wisc.edu/imr/statistics/imrstats.html">IMR Web Server Statistics</A><BR><!WA41><!WA41><!WA41><!WA41><!WA41><!WA41><!WA41><!WA41><!WA41><A HREF="http://www.bocklabs.wisc.edu/mbinfo/cnotes/info.html"><!WA42><!WA42><!WA42><!WA42><!WA42><!WA42><!WA42><!WA42><!WA42><IMG SRC="http://www.bocklabs.wisc.edu/imr/icons/ball-red.gif"></A><!WA43><!WA43><!WA43><!WA43><!WA43><!WA43><!WA43><!WA43><!WA43><A HREF="http://www.bocklabs.wisc.edu/mbinfo/cnotes/info.html">MB/IMR Computing Information</a><BR><HR> <H3 ALIGN=CENTER>Directory of Microscopists on the Internet</H3><!WA44><!WA44><!WA44><!WA44><!WA44><!WA44><!WA44><!WA44><!WA44><A HREF="http://www.bocklabs.wisc.edu/imr/microscopists.html"><!WA45><!WA45><!WA45><!WA45><!WA45><!WA45><!WA45><!WA45><!WA45><IMG SRC="http://www.bocklabs.wisc.edu/imr/icons/ball-red.gif"></A><!WA46><!WA46><!WA46><!WA46><!WA46><!WA46><!WA46><!WA46><!WA46><A HREF="http://www.bocklabs.wisc.edu/imr/microscopists.html">Directory of Microscopists on the Net</A><BR><!WA47><!WA47><!WA47><!WA47><!WA47><!WA47><!WA47><!WA47><!WA47><A HREF="http://www.bocklabs.wisc.edu/imr/microscopist-entry"><!WA48><!WA48><!WA48><!WA48><!WA48><!WA48><!WA48><!WA48><!WA48><IMG SRC="http://www.bocklabs.wisc.edu/imr/icons/ball-red.gif"></A> <!WA49><!WA49><!WA49><!WA49><!WA49><!WA49><!WA49><!WA49><!WA49><A HREF="http://www.bocklabs.wisc.edu/imr/microscopist-entry.html">Microscopists on the Net - Entry Form</A><HR SIZE=4><CENTER>Integrated Microscopy Resource<BR>1675 Observatory Drive<BR>University of Wisconsin<BR>Madison, WI  53706-1205<BR></P>General Information: (608) 265-3083<BR>Optical Microscopy:  (608) 263-6288<BR>Electron Microscopy: (608) 263-8481<BR><BR>Resource Fax:  (608) 265-4076<BR>Resource Email: <!WA50><!WA50><!WA50><!WA50><!WA50><!WA50><!WA50><!WA50><!WA50><A HREF="mailto:imradmin@calshp.cals.wisc.edu">imradmin@calshp.cals.wisc.edu</A><BR></P><BR><HR><BR>This page is currently maintained by Dawn N. Volkman and Kevin Eliceiri.  If you have questions, concerns, or suggestions, email us at <!WA51><!WA51><!WA51><!WA51><!WA51><!WA51><!WA51><!WA51><!WA51><A HREF="mailto:dvolkman@students.wisc.edu">dvolkman@students.wisc.edu</A>.<BR>For the history of this web page -- <!WA52><!WA52><!WA52><!WA52><!WA52><!WA52><!WA52><!WA52><!WA52><A HREF="http://www.bocklabs.wisc.edu/imr/webhis.html">click here</A>.<BR><HR><!WA53><!WA53><!WA53><!WA53><!WA53><!WA53><!WA53><!WA53><!WA53><A HREF="http://www.bocklabs.wisc.edu/mbinfo/mbinfo.html">Return to Molecular Biology Home Page</A></CENTER></BODY> </HTML><p>

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