sint4.dh

mfold

-14.30-11.90-13.70-12.60-15.00-11.90-15.20-11.50-16.70-10.70-16.30-12.60-15.20-11.90-15.20-10.70 
-14.60-12.20-14.00-12.90-15.30-12.20-15.50-11.80-17.00-11.00-16.60-12.90-15.50-12.20-15.50-11.00 
-13.40-11.00-12.80-11.70-14.10-11.00-14.30-10.60-15.80 -9.80-15.40-11.70-14.30-11.00-14.30 -9.80 
-14.60-12.20-14.00-12.90-15.30-12.20-15.50-11.80-17.00-11.00-16.60-12.90-15.50-12.20-15.50-11.00 
-12.20 -9.80-11.60-10.50-12.90 -9.80-13.10 -9.40-14.60 -8.60-14.20-10.50-13.10 -9.80-13.10 -8.60 
-12.20 -9.80-11.60-10.50-12.90 -9.80-13.10 -9.40-14.60 -8.60-14.20-10.50-13.10 -9.80-13.10 -8.60 
-12.20 -9.80-11.60-10.50-12.90 -9.80-13.10 -9.40-14.60 -8.60-14.20-10.50-13.10 -9.80-13.10 -8.60 
-12.90-10.50-12.30-11.20-13.60-10.50-13.80-10.10-15.30 -9.30-14.90-11.20-13.80-10.50-13.80 -9.30 
 
                                               Y 
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    A     A     A     A     C     C     C     C     G     G     G     G     U     U     U     U   
    A     C     G     U     A     C     G     U     A     C     G     U     A     C     G     U   
   --------------------------------------------------------------------------------------------- 
                                          5' ------> 3' 
                                           G \/ \_/ U 
                                           C /\  |  G 
                                          3' <------ 5' 
 -9.50 -7.80 -8.60 -8.50-11.20 -7.60-12.10 -8.50-11.20 -7.60-12.10 -8.50-11.20 -7.60-12.10 -8.50 
-13.10-11.40-12.20-12.10-14.80-11.20-15.70-12.10-14.80-11.20-15.70-12.10-14.80-11.20-15.70-12.10 
 -9.90 -8.20 -9.00 -8.90-11.60 -8.00-12.50 -8.90-11.60 -8.00-12.50 -8.90-11.60 -8.00-12.50 -8.90 
-13.10-11.40-12.20-12.10-14.80-11.20-15.70-12.10-14.80-11.20-15.70-12.10-14.80-11.20-15.70-12.10 
-11.50 -9.80-10.60-10.50-13.20 -9.60-14.10-10.50-13.20 -9.60-14.10-10.50-13.20 -9.60-14.10-10.50 
 -7.40 -5.70 -6.50 -6.40 -9.10 -5.50-10.00 -6.40 -9.10 -5.50-10.00 -6.40 -9.10 -5.50-10.00 -6.40 
 -7.40 -5.70 -6.50 -6.40 -9.10 -5.50-10.00 -6.40 -9.10 -5.50-10.00 -6.40 -9.10 -5.50-10.00 -6.40 
 -8.20 -6.50 -7.30 -7.20 -9.90 -6.30-10.80 -7.20 -9.90 -6.30-10.80 -7.20 -9.90 -6.30-10.80 -7.20 
-11.40 -9.70-10.50-10.40-13.10 -9.50-14.00-10.40-13.10 -9.50-14.00-10.40-13.10 -9.50-14.00-10.40 
-11.70-10.00-10.80-10.70-13.40 -9.80-14.30-10.70-13.40 -9.80-14.30-10.70-13.40 -9.80-14.30-10.70 
-10.50 -8.80 -9.60 -9.50-12.20 -8.60-13.10 -9.50-12.20 -8.60-13.10 -9.50-12.20 -8.60-13.10 -9.50 
-11.70-10.00-10.80-10.70-13.40 -9.80-14.30-10.70-13.40 -9.80-14.30-10.70-13.40 -9.80-14.30-10.70 
 -9.30 -7.60 -8.40 -8.30-11.00 -7.40-11.90 -8.30-11.00 -7.40-11.90 -8.30-11.00 -7.40-11.90 -8.30 
 -9.30 -7.60 -8.40 -8.30-11.00 -7.40-11.90 -8.30-11.00 -7.40-11.90 -8.30-11.00 -7.40-11.90 -8.30 
 -9.30 -7.60 -8.40 -8.30-11.00 -7.40-11.90 -8.30-11.00 -7.40-11.90 -8.30-11.00 -7.40-11.90 -8.30 
-10.00 -8.30 -9.10 -9.00-11.70 -8.10-12.60 -9.00-11.70 -8.10-12.60 -9.00-11.70 -8.10-12.60 -9.00 
 
                                               Y 
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    A     A     A     A     C     C     C     C     G     G     G     G     U     U     U     U   
    A     C     G     U     A     C     G     U     A     C     G     U     A     C     G     U   
   --------------------------------------------------------------------------------------------- 
                                          5' ------> 3' 
                                           U \/ \_/ A 
                                           A /\  |  U 
                                          3' <------ 5' 
 -8.00 -8.30 -7.80 -6.80-10.30 -9.10-10.80 -5.40-12.90 -6.00-12.90 -6.80 -9.90 -5.80-10.80 -5.40 
-10.30-10.60-10.10 -9.10-12.60-11.40-13.10 -7.70-15.20 -8.30-15.20 -9.10-12.20 -8.10-13.10 -7.70 
-12.90-13.20-12.70-11.70-15.20-14.00-15.70-10.30-17.80-10.90-17.80-11.70-14.80-10.70-15.70-10.30 
 -9.90-10.20 -9.70 -8.70-12.20-11.00-12.70 -7.30-14.80 -7.90-14.80 -8.70-11.80 -7.70-12.70 -7.30 
 -8.30 -8.60 -8.10 -7.10-10.60 -9.40-11.10 -5.70-13.20 -6.30-13.20 -7.10-10.20 -6.10-11.10 -5.70 
 -9.10 -9.40 -8.90 -7.90-11.40-10.20-11.90 -6.50-14.00 -7.10-14.00 -7.90-11.00 -6.90-11.90 -6.50 
 -6.00 -6.30 -5.80 -4.80 -8.30 -7.10 -8.80 -3.40-10.90 -4.00-10.90 -4.80 -7.90 -3.80 -8.80 -3.40 
 -5.80 -6.10 -5.60 -4.60 -8.10 -6.90 -8.60 -3.20-10.70 -3.80-10.70 -4.60 -7.70 -3.60 -8.60 -3.20 
 -7.80 -8.10 -7.60 -6.60-10.10 -8.90-10.60 -5.20-12.70 -5.80-12.70 -6.60 -9.70 -5.60-10.60 -5.20 
-10.80-11.10-10.60 -9.60-13.10-11.90-13.60 -8.20-15.70 -8.80-15.70 -9.60-12.70 -8.60-13.60 -8.20 
-12.90-13.20-12.70-11.70-15.20-14.00-15.70-10.30-17.80-10.90-17.80-11.70-14.80-10.70-15.70-10.30 
-10.80-11.10-10.60 -9.60-13.10-11.90-13.60 -8.20-15.70 -8.80-15.70 -9.60-12.70 -8.60-13.60 -8.20 
 -6.80 -7.10 -6.60 -5.60 -9.10 -7.90 -9.60 -4.20-11.70 -4.80-11.70 -5.60 -8.70 -4.60 -9.60 -4.20 
 -5.40 -5.70 -5.20 -4.20 -7.70 -6.50 -8.20 -2.80-10.30 -3.40-10.30 -4.20 -7.30 -3.20 -8.20 -2.80 
 -6.80 -7.10 -6.60 -5.60 -9.10 -7.90 -9.60 -4.20-11.70 -4.80-11.70 -5.60 -8.70 -4.60 -9.60 -4.20 
 -5.40 -5.70 -5.20 -4.20 -7.70 -6.50 -8.20 -2.80-10.30 -3.40-10.30 -4.20 -7.30 -3.20 -8.20 -2.80 
 
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    A     A     A     A     C     C     C     C     G     G     G     G     U     U     U     U   
    A     C     G     U     A     C     G     U     A     C     G     U     A     C     G     U   
   --------------------------------------------------------------------------------------------- 
                                          5' ------> 3' 
                                           U \/ \_/ C 
                                           A /\  |  G 
                                          3' <------ 5' 
 -9.20-11.20-11.10 -9.00-12.80 -7.10-11.40 -9.00 -9.60 -7.10-10.20 -9.00-12.80 -7.90-11.40 -9.70 
-11.50-13.50-13.40-11.30-15.10 -9.40-13.70-11.30-11.90 -9.40-12.50-11.30-15.10-10.20-13.70-12.00 
-14.10-16.10-16.00-13.90-17.70-12.00-16.30-13.90-14.50-12.00-15.10-13.90-17.70-12.80-16.30-14.60 
-11.10-13.10-13.00-10.90-14.70 -9.00-13.30-10.90-11.50 -9.00-12.10-10.90-14.70 -9.80-13.30-11.60 
 -9.50-11.50-11.40 -9.30-13.10 -7.40-11.70 -9.30 -9.90 -7.40-10.50 -9.30-13.10 -8.20-11.70-10.00 
-10.30-12.30-12.20-10.10-13.90 -8.20-12.50-10.10-10.70 -8.20-11.30-10.10-13.90 -9.00-12.50-10.80 
 -7.20 -9.20 -9.10 -7.00-10.80 -5.10 -9.40 -7.00 -7.60 -5.10 -8.20 -7.00-10.80 -5.90 -9.40 -7.70 
 -7.00 -9.00 -8.90 -6.80-10.60 -4.90 -9.20 -6.80 -7.40 -4.90 -8.00 -6.80-10.60 -5.70 -9.20 -7.50 
 -9.00-11.00-10.90 -8.80-12.60 -6.90-11.20 -8.80 -9.40 -6.90-10.00 -8.80-12.60 -7.70-11.20 -9.50 
-12.00-14.00-13.90-11.80-15.60 -9.90-14.20-11.80-12.40 -9.90-13.00-11.80-15.60-10.70-14.20-12.50 
-14.10-16.10-16.00-13.90-17.70-12.00-16.30-13.90-14.50-12.00-15.10-13.90-17.70-12.80-16.30-14.60 
-12.00-14.00-13.90-11.80-15.60 -9.90-14.20-11.80-12.40 -9.90-13.00-11.80-15.60-10.70-14.20-12.50 
 -8.00-10.00 -9.90 -7.80-11.60 -5.90-10.20 -7.80 -8.40 -5.90 -9.00 -7.80-11.60 -6.70-10.20 -8.50 
 -6.60 -8.60 -8.50 -6.40-10.20 -4.50 -8.80 -6.40 -7.00 -4.50 -7.60 -6.40-10.20 -5.30 -8.80 -7.10 
 -8.00-10.00 -9.90 -7.80-11.60 -5.90-10.20 -7.80 -8.40 -5.90 -9.00 -7.80-11.60 -6.70-10.20 -8.50 
 -6.60 -8.60 -8.50 -6.40-10.20 -4.50 -8.80 -6.40 -7.00 -4.50 -7.60 -6.40-10.20 -5.30 -8.80 -7.10 
 
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    A     A     A     A     C     C     C     C     G     G     G     G     U     U     U     U   
    A     C     G     U     A     C     G     U     A     C     G     U     A     C     G     U   
   --------------------------------------------------------------------------------------------- 
                                          5' ------> 3' 
                                           U \/ \_/ G 
                                           A /\  |  C 
                                          3' <------ 5' 
 -3.70 -9.20-13.40-12.10  5.50 -8.50-13.40-11.40  6.30 -9.20-13.40-12.10-14.30-10.70-13.40-12.60 
 -6.00-11.50-15.70-14.40  3.20-10.80-15.70-13.70  4.00-11.50-15.70-14.40-16.60-13.00-15.70-14.90 
 -8.60-14.10-18.30-17.00  0.60-13.40-18.30-16.30  1.40-14.10-18.30-17.00-19.20-15.60-18.30-17.50 
 -5.60-11.10-15.30-14.00  3.60-10.40-15.30-13.30  4.40-11.10-15.30-14.00-16.20-12.60-15.30-14.50 
 -4.00 -9.50-13.70-12.40  5.20 -8.80-13.70-11.70  6.00 -9.50-13.70-12.40-14.60-11.00-13.70-12.90 
 -4.80-10.30-14.50-13.20  4.40 -9.60-14.50-12.50  5.20-10.30-14.50-13.20-15.40-11.80-14.50-13.70 
 -1.70 -7.20-11.40-10.10  7.50 -6.50-11.40 -9.40  8.30 -7.20-11.40-10.10-12.30 -8.70-11.40-10.60 
 -1.50 -7.00-11.20 -9.90  7.70 -6.30-11.20 -9.20  8.50 -7.00-11.20 -9.90-12.10 -8.50-11.20-10.40 
 -3.50 -9.00-13.20-11.90  5.70 -8.30-13.20-11.20  6.50 -9.00-13.20-11.90-14.10-10.50-13.20-12.40 
 -6.50-12.00-16.20-14.90  2.70-11.30-16.20-14.20  3.50-12.00-16.20-14.90-17.10-13.50-16.20-15.40 
 -8.60-14.10-18.30-17.00  0.60-13.40-18.30-16.30  1.40-14.10-18.30-17.00-19.20-15.60-18.30-17.50 
 -6.50-12.00-16.20-14.90  2.70-11.30-16.20-14.20  3.50-12.00-16.20-14.90-17.10-13.50-16.20-15.40 
 -2.50 -8.00-12.20-10.90  6.70 -7.30-12.20-10.20  7.50 -8.00-12.20-10.90-13.10 -9.50-12.20-11.40 
 -1.10 -6.60-10.80 -9.50  8.10 -5.90-10.80 -8.80  8.90 -6.60-10.80 -9.50-11.70 -8.10-10.80-10.00 
 -2.50 -8.00-12.20-10.90  6.70 -7.30-12.20-10.20  7.50 -8.00-12.20-10.90-13.10 -9.50-12.20-11.40 
 -1.10 -6.60-10.80 -9.50  8.10 -5.90-10.80 -8.80  8.90 -6.60-10.80 -9.50-11.70 -8.10-10.80-10.00 
 
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    A     A     A     A     C     C     C     C     G     G     G     G     U     U     U     U   
    A     C     G     U     A     C     G     U     A     C     G     U     A     C     G     U   
   --------------------------------------------------------------------------------------------- 
                                          5' ------> 3' 
                                           U \/ \_/ U 
                                           A /\  |  A 
                                          3' <------ 5' 
 -8.30 -6.60 -7.40 -7.30-10.00 -6.40-10.90 -7.30-10.00 -6.40-10.90 -7.30-10.00 -6.40-10.90 -7.30 
-10.60 -8.90 -9.70 -9.60-12.30 -8.70-13.20 -9.60-12.30 -8.70-13.20 -9.60-12.30 -8.70-13.20 -9.60 
-13.20-11.50-12.30-12.20-14.90-11.30-15.80-12.20-14.90-11.30-15.80-12.20-14.90-11.30-15.80-12.20 
-10.20 -8.50 -9.30 -9.20-11.90 -8.30-12.80 -9.20-11.90 -8.30-12.80 -9.20-11.90 -8.30-12.80 -9.20 
 -8.60 -6.90 -7.70 -7.60-10.30 -6.70-11.20 -7.60-10.30 -6.70-11.20 -7.60-10.30 -6.70-11.20 -7.60 
 -9.40 -7.70 -8.50 -8.40-11.10 -7.50-12.00 -8.40-11.10 -7.50-12.00 -8.40-11.10 -7.50-12.00 -8.40 
 -6.30 -4.60 -5.40 -5.30 -8.00 -4.40 -8.90 -5.30 -8.00 -4.40 -8.90 -5.30 -8.00 -4.40 -8.90 -5.30 
 -6.10 -4.40 -5.20 -5.10 -7.80 -4.20 -8.70 -5.10 -7.80 -4.20 -8.70 -5.10 -7.80 -4.20 -8.70 -5.10 
 -8.10 -6.40 -7.20 -7.10 -9.80 -6.20-10.70 -7.10 -9.80 -6.20-10.70 -7.10 -9.80 -6.20-10.70 -7.10 
-11.10 -9.40-10.20-10.10-12.80 -9.20-13.70-10.10-12.80 -9.20-13.70-10.10-12.80 -9.20-13.70-10.10 
-13.20-11.50-12.30-12.20-14.90-11.30-15.80-12.20-14.90-11.30-15.80-12.20-14.90-11.30-15.80-12.20 
-11.10 -9.40-10.20-10.10-12.80 -9.20-13.70-10.10-12.80 -9.20-13.70-10.10-12.80 -9.20-13.70-10.10 
 -7.10 -5.40 -6.20 -6.10 -8.80 -5.20 -9.70 -6.10 -8.80 -5.20 -9.70 -6.10 -8.80 -5.20 -9.70 -6.10 
 -5.70 -4.00 -4.80 -4.70 -7.40 -3.80 -8.30 -4.70 -7.40 -3.80 -8.30 -4.70 -7.40 -3.80 -8.30 -4.70 
 -7.10 -5.40 -6.20 -6.10 -8.80 -5.20 -9.70 -6.10 -8.80 -5.20 -9.70 -6.10 -8.80 -5.20 -9.70 -6.10 
 -5.70 -4.00 -4.80 -4.70 -7.40 -3.80 -8.30 -4.70 -7.40 -3.80 -8.30 -4.70 -7.40 -3.80 -8.30 -4.70 
 
                                               Y 
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    A     A     A     A     C     C     C     C     G     G     G     G     U     U     U     U   
    A     C     G     U     A     C     G     U     A     C     G     U     A     C     G     U   
   --------------------------------------------------------------------------------------------- 
                                          5' ------> 3' 
                                           U \/ \_/ G 
                                           A /\  |  U 
                                          3' <------ 5' 
-11.20 -8.80-10.60 -9.50-11.90 -8.80-12.10 -8.40-13.60 -7.60-13.20 -9.50-12.10 -8.80-12.10 -7.60 
-13.50-11.10-12.90-11.80-14.20-11.10-14.40-10.70-15.90 -9.90-15.50-11.80-14.40-11.10-14.40 -9.90 
-16.10-13.70-15.50-14.40-16.80-13.70-17.00-13.30-18.50-12.50-18.10-14.40-17.00-13.70-17.00-12.50 
-13.10-10.70-12.50-11.40-13.80-10.70-14.00-10.30-15.50 -9.50-15.10-11.40-14.00-10.70-14.00 -9.50 
-11.50 -9.10-10.90 -9.80-12.20 -9.10-12.40 -8.70-13.90 -7.90-13.50 -9.80-12.40 -9.10-12.40 -7.90 
-12.30 -9.90-11.70-10.60-13.00 -9.90-13.20 -9.50-14.70 -8.70-14.30-10.60-13.20 -9.90-13.20 -8.70 
 -9.20 -6.80 -8.60 -7.50 -9.90 -6.80-10.10 -6.40-11.60 -5.60-11.20 -7.50-10.10 -6.80-10.10 -5.60