sint4.dh

mfold

-16.60-14.20-16.00-14.90-17.30-14.20-17.50-13.80-19.00-13.00-18.60-14.90-17.50-14.20-17.50-13.00 
-16.60-14.20-16.00-14.90-17.30-14.20-17.50-13.80-19.00-13.00-18.60-14.90-17.50-14.20-17.50-13.00 
-16.60-14.20-16.00-14.90-17.30-14.20-17.50-13.80-19.00-13.00-18.60-14.90-17.50-14.20-17.50-13.00 
-15.30-12.90-14.70-13.60-16.00-12.90-16.20-12.50-17.70-11.70-17.30-13.60-16.20-12.90-16.20-11.70 
-14.60-12.20-14.00-12.90-15.30-12.20-15.50-11.80-17.00-11.00-16.60-12.90-15.50-12.20-15.50-11.00 
-15.30-12.90-14.70-13.60-16.00-12.90-16.20-12.50-17.70-11.70-17.30-13.60-16.20-12.90-16.20-11.70 
-15.80-13.40-15.20-14.10-16.50-13.40-16.70-13.00-18.20-12.20-17.80-14.10-16.70-13.40-16.70-12.20 
 
                                               Y 
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    A     A     A     A     C     C     C     C     G     G     G     G     U     U     U     U   
    A     C     G     U     A     C     G     U     A     C     G     U     A     C     G     U   
   --------------------------------------------------------------------------------------------- 
                                          5' ------> 3' 
                                           C \/ \_/ U 
                                           G /\  |  G 
                                          3' <------ 5' 
 -4.00 -2.30 -3.10 -3.00 -5.70 -2.10 -6.60 -3.00 -5.70 -2.10 -6.60 -3.00 -5.70 -2.10 -6.60 -3.00 
  5.20  6.90  6.10  6.20  3.50  7.10  2.60  6.20  3.50  7.10  2.60  6.20  3.50  7.10  2.60  6.20 
  6.00  7.70  6.90  7.00  4.30  7.90  3.40  7.00  4.30  7.90  3.40  7.00  4.30  7.90  3.40  7.00 
-14.60-12.90-13.70-13.60-16.30-12.70-17.20-13.60-16.30-12.70-17.20-13.60-16.30-12.70-17.20-13.60 
 -9.50 -7.80 -8.60 -8.50-11.20 -7.60-12.10 -8.50-11.20 -7.60-12.10 -8.50-11.20 -7.60-12.10 -8.50 
 -8.80 -7.10 -7.90 -7.80-10.50 -6.90-11.40 -7.80-10.50 -6.90-11.40 -7.80-10.50 -6.90-11.40 -7.80 
 -9.50 -7.80 -8.60 -8.50-11.20 -7.60-12.10 -8.50-11.20 -7.60-12.10 -8.50-11.20 -7.60-12.10 -8.50 
-11.00 -9.30-10.10-10.00-12.70 -9.10-13.60-10.00-12.70 -9.10-13.60-10.00-12.70 -9.10-13.60-10.00 
-13.70-12.00-12.80-12.70-15.40-11.80-16.30-12.70-15.40-11.80-16.30-12.70-15.40-11.80-16.30-12.70 
-13.70-12.00-12.80-12.70-15.40-11.80-16.30-12.70-15.40-11.80-16.30-12.70-15.40-11.80-16.30-12.70 
-13.70-12.00-12.80-12.70-15.40-11.80-16.30-12.70-15.40-11.80-16.30-12.70-15.40-11.80-16.30-12.70 
-13.70-12.00-12.80-12.70-15.40-11.80-16.30-12.70-15.40-11.80-16.30-12.70-15.40-11.80-16.30-12.70 
-12.40-10.70-11.50-11.40-14.10-10.50-15.00-11.40-14.10-10.50-15.00-11.40-14.10-10.50-15.00-11.40 
-11.70-10.00-10.80-10.70-13.40 -9.80-14.30-10.70-13.40 -9.80-14.30-10.70-13.40 -9.80-14.30-10.70 
-12.40-10.70-11.50-11.40-14.10-10.50-15.00-11.40-14.10-10.50-15.00-11.40-14.10-10.50-15.00-11.40 
-12.90-11.20-12.00-11.90-14.60-11.00-15.50-11.90-14.60-11.00-15.50-11.90-14.60-11.00-15.50-11.90 
 
                                               Y 
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    A     A     A     A     C     C     C     C     G     G     G     G     U     U     U     U   
    A     C     G     U     A     C     G     U     A     C     G     U     A     C     G     U   
   --------------------------------------------------------------------------------------------- 
                                          5' ------> 3' 
                                           G \/ \_/ A 
                                           C /\  |  U 
                                          3' <------ 5' 
 -9.20 -9.50 -9.00 -8.00-11.50-10.30-12.00 -6.60-14.10 -7.20-14.10 -8.00-11.10 -7.00-12.00 -6.60 
-12.80-13.10-12.60-11.60-15.10-13.90-15.60-10.20-17.70-10.80-17.70-11.60-14.70-10.60-15.60-10.20 
 -9.60 -9.90 -9.40 -8.40-11.90-10.70-12.40 -7.00-14.50 -7.60-14.50 -8.40-11.50 -7.40-12.40 -7.00 
-12.80-13.10-12.60-11.60-15.10-13.90-15.60-10.20-17.70-10.80-17.70-11.60-14.70-10.60-15.60-10.20 
-11.20-11.50-11.00-10.00-13.50-12.30-14.00 -8.60-16.10 -9.20-16.10-10.00-13.10 -9.00-14.00 -8.60 
 -7.10 -7.40 -6.90 -5.90 -9.40 -8.20 -9.90 -4.50-12.00 -5.10-12.00 -5.90 -9.00 -4.90 -9.90 -4.50 
 -7.10 -7.40 -6.90 -5.90 -9.40 -8.20 -9.90 -4.50-12.00 -5.10-12.00 -5.90 -9.00 -4.90 -9.90 -4.50 
 -7.90 -8.20 -7.70 -6.70-10.20 -9.00-10.70 -5.30-12.80 -5.90-12.80 -6.70 -9.80 -5.70-10.70 -5.30 
-11.10-11.40-10.90 -9.90-13.40-12.20-13.90 -8.50-16.00 -9.10-16.00 -9.90-13.00 -8.90-13.90 -8.50 
-11.40-11.70-11.20-10.20-13.70-12.50-14.20 -8.80-16.30 -9.40-16.30-10.20-13.30 -9.20-14.20 -8.80 
-10.20-10.50-10.00 -9.00-12.50-11.30-13.00 -7.60-15.10 -8.20-15.10 -9.00-12.10 -8.00-13.00 -7.60 
-11.40-11.70-11.20-10.20-13.70-12.50-14.20 -8.80-16.30 -9.40-16.30-10.20-13.30 -9.20-14.20 -8.80 
 -9.00 -9.30 -8.80 -7.80-11.30-10.10-11.80 -6.40-13.90 -7.00-13.90 -7.80-10.90 -6.80-11.80 -6.40 
 -9.00 -9.30 -8.80 -7.80-11.30-10.10-11.80 -6.40-13.90 -7.00-13.90 -7.80-10.90 -6.80-11.80 -6.40 
 -9.00 -9.30 -8.80 -7.80-11.30-10.10-11.80 -6.40-13.90 -7.00-13.90 -7.80-10.90 -6.80-11.80 -6.40 
 -9.70-10.00 -9.50 -8.50-12.00-10.80-12.50 -7.10-14.60 -7.70-14.60 -8.50-11.60 -7.50-12.50 -7.10 
 
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    A     A     A     A     C     C     C     C     G     G     G     G     U     U     U     U   
    A     C     G     U     A     C     G     U     A     C     G     U     A     C     G     U   
   --------------------------------------------------------------------------------------------- 
                                          5' ------> 3' 
                                           G \/ \_/ C 
                                           C /\  |  G 
                                          3' <------ 5' 
-10.40-12.40-12.30-10.20-14.00 -8.30-12.60-10.20-10.80 -8.30-11.40-10.20-14.00 -9.10-12.60-10.90 
-14.00-16.00-15.90-13.80-17.60-11.90-16.20-13.80-14.40-11.90-15.00-13.80-17.60-12.70-16.20-14.50 
-10.80-12.80-12.70-10.60-14.40 -8.70-13.00-10.60-11.20 -8.70-11.80-10.60-14.40 -9.50-13.00-11.30 
-14.00-16.00-15.90-13.80-17.60-11.90-16.20-13.80-14.40-11.90-15.00-13.80-17.60-12.70-16.20-14.50 
-12.40-14.40-14.30-12.20-16.00-10.30-14.60-12.20-12.80-10.30-13.40-12.20-16.00-11.10-14.60-12.90 
 -8.30-10.30-10.20 -8.10-11.90 -6.20-10.50 -8.10 -8.70 -6.20 -9.30 -8.10-11.90 -7.00-10.50 -8.80 
 -8.30-10.30-10.20 -8.10-11.90 -6.20-10.50 -8.10 -8.70 -6.20 -9.30 -8.10-11.90 -7.00-10.50 -8.80 
 -9.10-11.10-11.00 -8.90-12.70 -7.00-11.30 -8.90 -9.50 -7.00-10.10 -8.90-12.70 -7.80-11.30 -9.60 
-12.30-14.30-14.20-12.10-15.90-10.20-14.50-12.10-12.70-10.20-13.30-12.10-15.90-11.00-14.50-12.80 
-12.60-14.60-14.50-12.40-16.20-10.50-14.80-12.40-13.00-10.50-13.60-12.40-16.20-11.30-14.80-13.10 
-11.40-13.40-13.30-11.20-15.00 -9.30-13.60-11.20-11.80 -9.30-12.40-11.20-15.00-10.10-13.60-11.90 
-12.60-14.60-14.50-12.40-16.20-10.50-14.80-12.40-13.00-10.50-13.60-12.40-16.20-11.30-14.80-13.10 
-10.20-12.20-12.10-10.00-13.80 -8.10-12.40-10.00-10.60 -8.10-11.20-10.00-13.80 -8.90-12.40-10.70 
-10.20-12.20-12.10-10.00-13.80 -8.10-12.40-10.00-10.60 -8.10-11.20-10.00-13.80 -8.90-12.40-10.70 
-10.20-12.20-12.10-10.00-13.80 -8.10-12.40-10.00-10.60 -8.10-11.20-10.00-13.80 -8.90-12.40-10.70 
-10.90-12.90-12.80-10.70-14.50 -8.80-13.10-10.70-11.30 -8.80-11.90-10.70-14.50 -9.60-13.10-11.40 
 
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    A     A     A     A     C     C     C     C     G     G     G     G     U     U     U     U   
    A     C     G     U     A     C     G     U     A     C     G     U     A     C     G     U   
   --------------------------------------------------------------------------------------------- 
                                          5' ------> 3' 
                                           G \/ \_/ G 
                                           C /\  |  C 
                                          3' <------ 5' 
 -4.90-10.40-14.60-13.30  4.30 -9.70-14.60-12.60  5.10-10.40-14.60-13.30-15.50-11.90-14.60-13.80 
 -8.50-14.00-18.20-16.90  0.70-13.30-18.20-16.20  1.50-14.00-18.20-16.90-19.10-15.50-18.20-17.40 
 -5.30-10.80-15.00-13.70  3.90-10.10-15.00-13.00  4.70-10.80-15.00-13.70-15.90-12.30-15.00-14.20 
 -8.50-14.00-18.20-16.90  0.70-13.30-18.20-16.20  1.50-14.00-18.20-16.90-19.10-15.50-18.20-17.40 
 -6.90-12.40-16.60-15.30  2.30-11.70-16.60-14.60  3.10-12.40-16.60-15.30-17.50-13.90-16.60-15.80 
 -2.80 -8.30-12.50-11.20  6.40 -7.60-12.50-10.50  7.20 -8.30-12.50-11.20-13.40 -9.80-12.50-11.70 
 -2.80 -8.30-12.50-11.20  6.40 -7.60-12.50-10.50  7.20 -8.30-12.50-11.20-13.40 -9.80-12.50-11.70 
 -3.60 -9.10-13.30-12.00  5.60 -8.40-13.30-11.30  6.40 -9.10-13.30-12.00-14.20-10.60-13.30-12.50 
 -6.80-12.30-16.50-15.20  2.40-11.60-16.50-14.50  3.20-12.30-16.50-15.20-17.40-13.80-16.50-15.70 
 -7.10-12.60-16.80-15.50  2.10-11.90-16.80-14.80  2.90-12.60-16.80-15.50-17.70-14.10-16.80-16.00 
 -5.90-11.40-15.60-14.30  3.30-10.70-15.60-13.60  4.10-11.40-15.60-14.30-16.50-12.90-15.60-14.80 
 -7.10-12.60-16.80-15.50  2.10-11.90-16.80-14.80  2.90-12.60-16.80-15.50-17.70-14.10-16.80-16.00 
 -4.70-10.20-14.40-13.10  4.50 -9.50-14.40-12.40  5.30-10.20-14.40-13.10-15.30-11.70-14.40-13.60 
 -4.70-10.20-14.40-13.10  4.50 -9.50-14.40-12.40  5.30-10.20-14.40-13.10-15.30-11.70-14.40-13.60 
 -4.70-10.20-14.40-13.10  4.50 -9.50-14.40-12.40  5.30-10.20-14.40-13.10-15.30-11.70-14.40-13.60 
 -5.40-10.90-15.10-13.80  3.80-10.20-15.10-13.10  4.60-10.90-15.10-13.80-16.00-12.40-15.10-14.30 
 
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    A     A     A     A     C     C     C     C     G     G     G     G     U     U     U     U   
    A     C     G     U     A     C     G     U     A     C     G     U     A     C     G     U   
   --------------------------------------------------------------------------------------------- 
                                          5' ------> 3' 
                                           G \/ \_/ U 
                                           C /\  |  A 
                                          3' <------ 5' 
 -9.50 -7.80 -8.60 -8.50-11.20 -7.60-12.10 -8.50-11.20 -7.60-12.10 -8.50-11.20 -7.60-12.10 -8.50 
-13.10-11.40-12.20-12.10-14.80-11.20-15.70-12.10-14.80-11.20-15.70-12.10-14.80-11.20-15.70-12.10 
 -9.90 -8.20 -9.00 -8.90-11.60 -8.00-12.50 -8.90-11.60 -8.00-12.50 -8.90-11.60 -8.00-12.50 -8.90 
-13.10-11.40-12.20-12.10-14.80-11.20-15.70-12.10-14.80-11.20-15.70-12.10-14.80-11.20-15.70-12.10 
-11.50 -9.80-10.60-10.50-13.20 -9.60-14.10-10.50-13.20 -9.60-14.10-10.50-13.20 -9.60-14.10-10.50 
 -7.40 -5.70 -6.50 -6.40 -9.10 -5.50-10.00 -6.40 -9.10 -5.50-10.00 -6.40 -9.10 -5.50-10.00 -6.40 
 -7.40 -5.70 -6.50 -6.40 -9.10 -5.50-10.00 -6.40 -9.10 -5.50-10.00 -6.40 -9.10 -5.50-10.00 -6.40 
 -8.20 -6.50 -7.30 -7.20 -9.90 -6.30-10.80 -7.20 -9.90 -6.30-10.80 -7.20 -9.90 -6.30-10.80 -7.20 
-11.40 -9.70-10.50-10.40-13.10 -9.50-14.00-10.40-13.10 -9.50-14.00-10.40-13.10 -9.50-14.00-10.40 
-11.70-10.00-10.80-10.70-13.40 -9.80-14.30-10.70-13.40 -9.80-14.30-10.70-13.40 -9.80-14.30-10.70 
-10.50 -8.80 -9.60 -9.50-12.20 -8.60-13.10 -9.50-12.20 -8.60-13.10 -9.50-12.20 -8.60-13.10 -9.50 
-11.70-10.00-10.80-10.70-13.40 -9.80-14.30-10.70-13.40 -9.80-14.30-10.70-13.40 -9.80-14.30-10.70 
 -9.30 -7.60 -8.40 -8.30-11.00 -7.40-11.90 -8.30-11.00 -7.40-11.90 -8.30-11.00 -7.40-11.90 -8.30 
 -9.30 -7.60 -8.40 -8.30-11.00 -7.40-11.90 -8.30-11.00 -7.40-11.90 -8.30-11.00 -7.40-11.90 -8.30 
 -9.30 -7.60 -8.40 -8.30-11.00 -7.40-11.90 -8.30-11.00 -7.40-11.90 -8.30-11.00 -7.40-11.90 -8.30 
-10.00 -8.30 -9.10 -9.00-11.70 -8.10-12.60 -9.00-11.70 -8.10-12.60 -9.00-11.70 -8.10-12.60 -9.00 
 
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    A     A     A     A     C     C     C     C     G     G     G     G     U     U     U     U   
    A     C     G     U     A     C     G     U     A     C     G     U     A     C     G     U   
   --------------------------------------------------------------------------------------------- 
                                          5' ------> 3' 
                                           G \/ \_/ G 
                                           C /\  |  U 
                                          3' <------ 5' 
-12.40-10.00-11.80-10.70-13.10-10.00-13.30 -9.60-14.80 -8.80-14.40-10.70-13.30-10.00-13.30 -8.80 
-16.00-13.60-15.40-14.30-16.70-13.60-16.90-13.20-18.40-12.40-18.00-14.30-16.90-13.60-16.90-12.40 
-12.80-10.40-12.20-11.10-13.50-10.40-13.70-10.00-15.20 -9.20-14.80-11.10-13.70-10.40-13.70 -9.20 
-16.00-13.60-15.40-14.30-16.70-13.60-16.90-13.20-18.40-12.40-18.00-14.30-16.90-13.60-16.90-12.40 
-14.40-12.00-13.80-12.70-15.10-12.00-15.30-11.60-16.80-10.80-16.40-12.70-15.30-12.00-15.30-10.80 
-10.30 -7.90 -9.70 -8.60-11.00 -7.90-11.20 -7.50-12.70 -6.70-12.30 -8.60-11.20 -7.90-11.20 -6.70 
-10.30 -7.90 -9.70 -8.60-11.00 -7.90-11.20 -7.50-12.70 -6.70-12.30 -8.60-11.20 -7.90-11.20 -6.70 
-11.10 -8.70-10.50 -9.40-11.80 -8.70-12.00 -8.30-13.50 -7.50-13.10 -9.40-12.00 -8.70-12.00 -7.50