matrix_freq_ratios.c

ncbi源码

{0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.003},
{0.003, 0.003, 0.003, 0.003, 0.003, 0.003, 0.003, 0.003, 0.003, 0.003, 0.003, 0.003, 0.003, 0.003, 0.003, 0.003, 0.003, 0.003, 0.003, 0.003, 0.003, 0.003, 0.003, 0.003, 0.003, 1.333},
};

static const double PAM70_FREQRATIOS[BLASTAA_SIZE][BLASTAA_SIZE] = {
{0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.002},
{0.000, 4.900, 0.605, 0.242, 0.619, 0.771, 0.135, 1.015, 0.221, 0.434, 0.249, 0.250, 0.376, 0.589, 1.030, 0.466, 0.227, 1.350, 1.327, 0.809, 0.043, 0.750, 0.154, 0.638, 0.000, 0.002},
{0.000, 0.605, 5.422, 0.066, 5.890, 2.249, 0.079, 0.649, 1.099, 0.253, 0.778, 0.120, 0.140, 4.879, 0.274, 0.790, 0.253, 0.955, 0.654, 0.185, 0.078, 0.750, 0.223, 1.613, 0.000, 0.002},
{0.000, 0.242, 0.066, 24.836, 0.040, 0.039, 0.055, 0.116, 0.165, 0.246, 0.038, 0.030, 0.044, 0.097, 0.159, 0.039, 0.151, 0.665, 0.186, 0.274, 0.022, 0.750, 0.523, 0.039, 0.000, 0.002},
{0.000, 0.618, 5.890, 0.040, 8.900, 3.357, 0.034, 0.639, 0.600, 0.193, 0.484, 0.064, 0.103, 2.400, 0.213, 0.922, 0.139, 0.600, 0.442, 0.173, 0.026, 0.750, 0.080, 2.296, 0.000, 0.002},
{0.000, 0.771, 2.249, 0.039, 3.357, 8.654, 0.038, 0.492, 0.480, 0.284, 0.466, 0.117, 0.212, 0.965, 0.347, 2.258, 0.179, 0.479, 0.338, 0.247, 0.019, 0.750, 0.119, 5.867, 0.000, 0.002},
{0.000, 0.135, 0.079, 0.055, 0.034, 0.038, 17.455, 0.100, 0.277, 0.846, 0.041, 0.824, 0.508, 0.131, 0.089, 0.052, 0.099, 0.216, 0.138, 0.208, 0.452, 0.750, 3.378, 0.044, 0.000, 0.002},
{0.000, 1.015, 0.649, 0.116, 0.639, 0.492, 0.100, 7.309, 0.145, 0.107, 0.210, 0.081, 0.144, 0.660, 0.308, 0.237, 0.122, 0.964, 0.370, 0.313, 0.027, 0.750, 0.044, 0.381, 0.000, 0.002},
{0.000, 0.221, 1.099, 0.165, 0.600, 0.480, 0.277, 0.145, 16.422, 0.140, 0.335, 0.259, 0.122, 1.677, 0.493, 2.188, 1.058, 0.327, 0.230, 0.233, 0.186, 0.750, 0.611, 1.224, 0.000, 0.002},
{0.000, 0.434, 0.253, 0.246, 0.193, 0.284, 0.846, 0.107, 0.140, 11.749, 0.266, 1.192, 1.369, 0.322, 0.160, 0.189, 0.301, 0.254, 0.761, 3.004, 0.044, 0.750, 0.281, 0.242, 0.000, 0.002},
{0.000, 0.249, 0.778, 0.038, 0.484, 0.466, 0.041, 0.210, 0.335, 0.266, 7.610, 0.153, 0.948, 1.119, 0.256, 0.722, 1.937, 0.520, 0.620, 0.139, 0.079, 0.750, 0.101, 0.578, 0.000, 0.002},
{0.000, 0.250, 0.120, 0.030, 0.064, 0.117, 0.824, 0.081, 0.259, 1.192, 0.153, 8.228, 2.130, 0.185, 0.199, 0.351, 0.137, 0.149, 0.240, 0.908, 0.267, 0.750, 0.239, 0.219, 0.000, 0.002},
{0.000, 0.376, 0.140, 0.044, 0.103, 0.212, 0.508, 0.144, 0.122, 1.369, 0.948, 2.129, 28.592, 0.182, 0.176, 0.486, 0.488, 0.319, 0.498, 1.133, 0.060, 0.750, 0.097, 0.332, 0.000, 0.002},
{0.000, 0.589, 4.879, 0.097, 2.400, 0.965, 0.131, 0.660, 1.677, 0.322, 1.119, 0.185, 0.182, 7.754, 0.344, 0.637, 0.387, 1.366, 0.899, 0.199, 0.138, 0.750, 0.390, 0.822, 0.000, 0.002},
{0.000, 1.030, 0.274, 0.159, 0.213, 0.347, 0.089, 0.308, 0.493, 0.160, 0.256, 0.199, 0.176, 0.344, 11.871, 0.684, 0.527, 0.979, 0.531, 0.307, 0.042, 0.750, 0.047, 0.494, 0.000, 0.002},
{0.000, 0.466, 0.790, 0.039, 0.923, 2.258, 0.052, 0.237, 2.188, 0.189, 0.722, 0.351, 0.486, 0.637, 0.684, 11.469, 1.024, 0.373, 0.329, 0.232, 0.055, 0.750, 0.074, 6.272, 0.000, 0.002},
{0.000, 0.227, 0.253, 0.151, 0.139, 0.179, 0.099, 0.122, 1.058, 0.301, 1.937, 0.137, 0.488, 0.387, 0.527, 1.024, 13.660, 0.610, 0.284, 0.176, 0.991, 0.750, 0.086, 0.547, 0.000, 0.002},
{0.000, 1.350, 0.955, 0.665, 0.600, 0.479, 0.216, 0.964, 0.327, 0.254, 0.520, 0.149, 0.319, 1.366, 0.979, 0.373, 0.610, 5.204, 1.695, 0.303, 0.324, 0.750, 0.208, 0.433, 0.000, 0.002},
{0.000, 1.327, 0.654, 0.186, 0.442, 0.338, 0.138, 0.370, 0.230, 0.761, 0.620, 0.240, 0.498, 0.899, 0.531, 0.329, 0.284, 1.695, 7.337, 0.719, 0.055, 0.750, 0.228, 0.334, 0.000, 0.002},
{0.000, 0.809, 0.185, 0.275, 0.173, 0.247, 0.208, 0.313, 0.233, 3.003, 0.139, 0.908, 1.133, 0.199, 0.307, 0.232, 0.176, 0.303, 0.719, 8.211, 0.027, 0.750, 0.181, 0.240, 0.000, 0.002},
{0.000, 0.043, 0.078, 0.022, 0.026, 0.019, 0.452, 0.027, 0.186, 0.044, 0.079, 0.267, 0.060, 0.138, 0.042, 0.055, 0.991, 0.324, 0.054, 0.027, 80.645, 0.750, 0.377, 0.035, 0.000, 0.002},
{0.000, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.000, 0.002},
{0.000, 0.154, 0.223, 0.523, 0.080, 0.119, 3.379, 0.044, 0.611, 0.281, 0.101, 0.239, 0.097, 0.390, 0.047, 0.074, 0.086, 0.208, 0.228, 0.181, 0.377, 0.750, 23.141, 0.099, 0.000, 0.002},
{0.000, 0.638, 1.613, 0.039, 2.296, 5.867, 0.044, 0.381, 1.224, 0.242, 0.578, 0.219, 0.332, 0.822, 0.494, 6.272, 0.547, 0.433, 0.334, 0.240, 0.035, 0.750, 0.099, 6.043, 0.000, 0.002},
{0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.002},
{0.002, 0.002, 0.002, 0.002, 0.002, 0.002, 0.002, 0.002, 0.002, 0.002, 0.002, 0.002, 0.002, 0.002, 0.002, 0.002, 0.002, 0.002, 0.002, 0.002, 0.002, 0.002, 0.002, 0.002, 0.002, 1.333},
};

static const double BLOSUM45_FREQRATIOS[BLASTAA_SIZE][BLASTAA_SIZE] = {
{0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.290},
{0.000, 2.950, 0.735, 0.800, 0.689, 0.825, 0.587, 1.080, 0.654, 0.747, 0.786, 0.712, 0.821, 0.789, 0.709, 0.867, 0.700, 1.300, 1.001, 1.010, 0.565, 0.750, 0.639, 0.841, 0.000, 0.290},
{0.000, 0.735, 3.260, 0.600, 3.594, 1.300, 0.496, 0.886, 1.088, 0.497, 1.023, 0.472, 0.580, 2.862, 0.686, 0.992, 0.829, 1.053, 0.985, 0.520, 0.381, 0.750, 0.627, 1.182, 0.000, 0.290},
{0.000, 0.800, 0.600, 17.090, 0.533, 0.545, 0.602, 0.557, 0.491, 0.543, 0.547, 0.673, 0.604, 0.680, 0.411, 0.486, 0.472, 0.797, 0.822, 0.715, 0.334, 0.750, 0.489, 0.523, 0.000, 0.290},
{0.000, 0.689, 3.594, 0.533, 5.356, 1.643, 0.431, 0.740, 0.976, 0.440, 0.942, 0.463, 0.494, 1.502, 0.724, 0.958, 0.771, 0.929, 0.876, 0.494, 0.373, 0.750, 0.645, 1.381, 0.000, 0.290},
{0.000, 0.825, 1.300, 0.545, 1.643, 3.873, 0.498, 0.576, 0.962, 0.485, 1.277, 0.571, 0.615, 0.893, 0.911, 1.531, 1.011, 0.912, 0.833, 0.555, 0.519, 0.750, 0.617, 2.978, 0.000, 0.290},
{0.000, 0.587, 0.496, 0.602, 0.431, 0.498, 5.748, 0.480, 0.679, 1.064, 0.529, 1.303, 1.063, 0.572, 0.451, 0.444, 0.590, 0.610, 0.716, 0.953, 1.355, 0.750, 2.185, 0.477, 0.000, 0.290},
{0.000, 1.080, 0.886, 0.557, 0.740, 0.576, 0.480, 5.071, 0.662, 0.416, 0.678, 0.450, 0.585, 1.059, 0.702, 0.687, 0.570, 1.058, 0.693, 0.479, 0.591, 0.750, 0.549, 0.619, 0.000, 0.290},
{0.000, 0.654, 1.088, 0.491, 0.976, 0.962, 0.679, 0.662, 9.512, 0.453, 0.890, 0.670, 0.918, 1.220, 0.661, 1.151, 0.973, 0.854, 0.706, 0.457, 0.452, 0.750, 1.472, 1.034, 0.000, 0.290},
{0.000, 0.747, 0.497, 0.543, 0.440, 0.485, 1.064, 0.416, 0.453, 3.233, 0.532, 1.596, 1.455, 0.564, 0.610, 0.578, 0.488, 0.618, 0.848, 2.176, 0.565, 0.750, 0.906, 0.521, 0.000, 0.290},
{0.000, 0.786, 1.023, 0.547, 0.942, 1.277, 0.529, 0.678, 0.890, 0.532, 3.327, 0.554, 0.738, 1.119, 0.781, 1.330, 1.943, 0.890, 0.885, 0.592, 0.562, 0.750, 0.737, 1.297, 0.000, 0.290},
{0.000, 0.712, 0.472, 0.673, 0.463, 0.571, 1.303, 0.450, 0.670, 1.596, 0.554, 2.997, 1.731, 0.484, 0.478, 0.642, 0.601, 0.556, 0.781, 1.334, 0.671, 0.750, 0.965, 0.598, 0.000, 0.290},
{0.000, 0.821, 0.580, 0.604, 0.494, 0.615, 1.063, 0.585, 0.918, 1.455, 0.738, 1.731, 4.114, 0.682, 0.644, 0.941, 0.776, 0.660, 0.860, 1.236, 0.634, 0.750, 1.023, 0.739, 0.000, 0.290},
{0.000, 0.789, 2.862, 0.680, 1.502, 0.893, 0.572, 1.059, 1.220, 0.564, 1.119, 0.484, 0.682, 4.478, 0.640, 1.032, 0.898, 1.200, 1.115, 0.552, 0.390, 0.750, 0.606, 0.946, 0.000, 0.290},
{0.000, 0.709, 0.686, 0.411, 0.724, 0.911, 0.451, 0.702, 0.661, 0.610, 0.781, 0.478, 0.644, 0.640, 8.819, 0.716, 0.582, 0.750, 0.856, 0.540, 0.525, 0.750, 0.479, 0.836, 0.000, 0.290},
{0.000, 0.867, 0.992, 0.486, 0.958, 1.531, 0.444, 0.687, 1.151, 0.578, 1.330, 0.642, 0.941, 1.032, 0.716, 4.407, 1.329, 1.092, 0.781, 0.547, 0.645, 0.750, 0.829, 2.630, 0.000, 0.290},
{0.000, 0.700, 0.829, 0.472, 0.771, 1.011, 0.590, 0.570, 0.973, 0.488, 1.943, 0.601, 0.776, 0.898, 0.582, 1.329, 4.747, 0.799, 0.715, 0.578, 0.580, 0.750, 0.807, 1.132, 0.000, 0.290},
{0.000, 1.300, 1.053, 0.797, 0.929, 0.912, 0.610, 1.058, 0.854, 0.618, 0.890, 0.556, 0.660, 1.200, 0.750, 1.092, 0.799, 2.782, 1.472, 0.728, 0.428, 0.750, 0.706, 0.981, 0.000, 0.290},
{0.000, 1.001, 0.985, 0.822, 0.876, 0.833, 0.716, 0.693, 0.706, 0.848, 0.885, 0.781, 0.860, 1.115, 0.856, 0.781, 0.715, 1.472, 3.139, 1.040, 0.454, 0.750, 0.744, 0.813, 0.000, 0.290},
{0.000, 1.010, 0.520, 0.715, 0.494, 0.555, 0.953, 0.479, 0.457, 2.176, 0.592, 1.334, 1.236, 0.552, 0.540, 0.547, 0.578, 0.728, 1.040, 2.871, 0.473, 0.750, 0.809, 0.552, 0.000, 0.290},
{0.000, 0.565, 0.381, 0.334, 0.373, 0.519, 1.355, 0.591, 0.452, 0.565, 0.562, 0.671, 0.634, 0.390, 0.525, 0.645, 0.580, 0.428, 0.454, 0.473, 29.702, 0.750, 1.801, 0.567, 0.000, 0.290},
{0.000, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.000, 0.290},
{0.000, 0.639, 0.627, 0.489, 0.645, 0.617, 2.185, 0.549, 1.472, 0.906, 0.737, 0.965, 1.023, 0.606, 0.479, 0.829, 0.807, 0.706, 0.744, 0.809, 1.801, 0.750, 5.753, 0.698, 0.000, 0.290},
{0.000, 0.841, 1.182, 0.523, 1.381, 2.978, 0.477, 0.619, 1.034, 0.521, 1.297, 0.598, 0.739, 0.946, 0.836, 2.630, 1.132, 0.981, 0.813, 0.552, 0.567, 0.750, 0.698, 2.845, 0.000, 0.290},
{0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.290},
{0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 1.333},
};

static const double BLOSUM80_FREQRATIOS[BLASTAA_SIZE][BLASTAA_SIZE] = {
{0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.140},
{0.000, 4.773, 0.477, 0.732, 0.451, 0.703, 0.397, 0.957, 0.514, 0.543, 0.723, 0.505, 0.625, 0.510, 0.771, 0.696, 0.555, 1.535, 0.980, 0.866, 0.309, 0.750, 0.436, 0.700, 0.000, 0.140},
{0.000, 0.477, 5.362, 0.252, 5.759, 1.269, 0.252, 0.639, 0.830, 0.234, 0.793, 0.221, 0.310, 4.868, 0.428, 0.850, 0.609, 0.948, 0.743, 0.268, 0.179, 0.750, 0.307, 1.109, 0.000, 0.140},
{0.000, 0.732, 0.252, 20.702, 0.214, 0.180, 0.395, 0.272, 0.221, 0.581, 0.241, 0.493, 0.499, 0.300, 0.269, 0.295, 0.233, 0.576, 0.602, 0.634, 0.302, 0.750, 0.308, 0.224, 0.000, 0.140},
{0.000, 0.451, 5.759, 0.214, 9.106, 1.635, 0.234, 0.541, 0.594, 0.214, 0.677, 0.197, 0.252, 1.584, 0.452, 0.763, 0.477, 0.774, 0.611, 0.245, 0.145, 0.750, 0.245, 1.303, 0.000, 0.140},
{0.000, 0.703, 1.269, 0.180, 1.635, 6.995, 0.249, 0.399, 0.901, 0.264, 1.195, 0.276, 0.429, 0.811, 0.581, 1.906, 0.832, 0.845, 0.685, 0.369, 0.241, 0.750, 0.333, 5.054, 0.000, 0.140},
{0.000, 0.397, 0.252, 0.395, 0.234, 0.249, 9.486, 0.249, 0.572, 0.841, 0.283, 1.114, 0.893, 0.273, 0.237, 0.285, 0.287, 0.369, 0.445, 0.649, 1.089, 0.750, 2.780, 0.263, 0.000, 0.140},
{0.000, 0.957, 0.639, 0.272, 0.541, 0.399, 0.249, 7.882, 0.387, 0.184, 0.483, 0.210, 0.286, 0.761, 0.347, 0.425, 0.377, 0.784, 0.492, 0.251, 0.264, 0.750, 0.230, 0.409, 0.000, 0.140},
{0.000, 0.514, 0.830, 0.221, 0.594, 0.901, 0.572, 0.387, 16.070, 0.258, 0.740, 0.314, 0.432, 1.124, 0.420, 1.316, 0.925, 0.661, 0.540, 0.289, 0.390, 0.750, 1.819, 1.059, 0.000, 0.140},
{0.000, 0.543, 0.234, 0.581, 0.214, 0.264, 0.841, 0.184, 0.258, 4.868, 0.313, 1.665, 1.512, 0.258, 0.286, 0.309, 0.299, 0.379, 0.701, 2.496, 0.343, 0.750, 0.539, 0.281, 0.000, 0.140},
{0.000, 0.723, 0.793, 0.241, 0.677, 1.195, 0.283, 0.483, 0.740, 0.313, 6.326, 0.357, 0.534, 0.938, 0.597, 1.524, 2.192, 0.820, 0.736, 0.370, 0.241, 0.750, 0.408, 1.320, 0.000, 0.140},
{0.000, 0.505, 0.221, 0.493, 0.197, 0.276, 1.114, 0.210, 0.314, 1.665, 0.357, 4.463, 2.123, 0.250, 0.303, 0.407, 0.363, 0.368, 0.561, 1.220, 0.439, 0.750, 0.581, 0.326, 0.000, 0.140},
{0.000, 0.625, 0.310, 0.499, 0.252, 0.429, 0.893, 0.286, 0.432, 1.512, 0.534, 2.123, 8.883, 0.382, 0.362, 0.887, 0.506, 0.498, 0.758, 1.224, 0.561, 0.750, 0.550, 0.603, 0.000, 0.140},
{0.000, 0.510, 4.868, 0.300, 1.584, 0.811, 0.273, 0.761, 1.124, 0.258, 0.938, 0.250, 0.382, 8.963, 0.398, 0.958, 0.773, 1.165, 0.908, 0.297, 0.221, 0.750, 0.385, 0.867, 0.000, 0.140},
{0.000, 0.771, 0.428, 0.269, 0.452, 0.581, 0.237, 0.347, 0.420, 0.286, 0.597, 0.303, 0.362, 0.398, 15.155, 0.538, 0.446, 0.652, 0.560, 0.370, 0.178, 0.750, 0.258, 0.565, 0.000, 0.140},
{0.000, 0.696, 0.850, 0.295, 0.763, 1.906, 0.285, 0.425, 1.316, 0.309, 1.524, 0.407, 0.887, 0.958, 0.538, 8.340, 1.394, 0.859, 0.724, 0.411, 0.408, 0.750, 0.462, 4.360, 0.000, 0.140},
{0.000, 0.555, 0.609, 0.233, 0.477, 0.832, 0.287, 0.377, 0.925, 0.299, 2.192, 0.363, 0.506, 0.773, 0.446, 1.394, 8.245, 0.695, 0.598, 0.354, 0.294, 0.750, 0.418, 1.046, 0.000, 0.140},
{0.000, 1.535, 0.948, 0.576, 0.774, 0.845, 0.369, 0.784, 0.661, 0.379, 0.820, 0.368, 0.498, 1.165, 0.652, 0.859, 0.695, 5.106, 1.663, 0.494, 0.271, 0.750, 0.462, 0.850, 0.000, 0.140},
{0.000, 0.980, 0.743, 0.602, 0.611, 0.685, 0.445, 0.492, 0.540, 0.701, 0.736, 0.561, 0.758, 0.908, 0.560, 0.724, 0.598, 1.663, 6.205, 0.891, 0.285, 0.750, 0.474, 0.700, 0.000, 0.140},
{0.000, 0.866, 0.268, 0.634, 0.245, 0.369, 0.649, 0.251, 0.289, 2.496, 0.370, 1.220, 1.224, 0.297, 0.370, 0.411, 0.354, 0.494, 0.891, 4.584, 0.342, 0.750, 0.489, 0.385, 0.000, 0.140},
{0.000, 0.309, 0.179, 0.302, 0.145, 0.241, 1.089, 0.264, 0.390, 0.343, 0.241, 0.439, 0.561, 0.221, 0.178, 0.408, 0.294, 0.271, 0.285, 0.342, 41.552, 0.750, 2.036, 0.304, 0.000, 0.140},
{0.000, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.000, 0.140},
{0.000, 0.436, 0.307, 0.308, 0.245, 0.333, 2.780, 0.230, 1.819, 0.539, 0.408, 0.581, 0.550, 0.385, 0.258, 0.462, 0.418, 0.462, 0.474, 0.489, 2.036, 0.750, 12.194, 0.382, 0.000, 0.140},
{0.000, 0.700, 1.109, 0.224, 1.303, 5.054, 0.263, 0.409, 1.059, 0.281, 1.320, 0.326, 0.603, 0.867, 0.565, 4.360, 1.046, 0.850, 0.700, 0.385, 0.304, 0.750, 0.382, 4.789, 0.000, 0.140},
{0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.140},
{0.140, 0.140, 0.140, 0.140, 0.140, 0.140, 0.140, 0.140, 0.140, 0.140, 0.140, 0.140, 0.140, 0.140, 0.140, 0.140, 0.140, 0.140, 0.140, 0.140, 0.140, 0.140, 0.140, 0.140, 0.140, 1.333},
};

static const double BLOSUM50_FREQRATIOS[BLASTAA_SIZE][BLASTAA_SIZE] = {
{0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.290},
{0.000, 3.273, 0.687, 0.888, 0.660, 0.797, 0.546, 1.101, 0.641, 0.715, 0.748, 0.657, 0.854, 0.720, 0.715, 0.820, 0.668, 1.364, 0.967, 0.982, 0.464, 0.750, 0.596, 0.806, 0.000, 0.290},
{0.000, 0.687, 3.676, 0.507, 4.021, 1.319, 0.384, 0.848, 1.118, 0.407, 0.968, 0.391, 0.516, 3.269, 0.661, 0.998, 0.759, 1.061, 0.955, 0.446, 0.339, 0.750, 0.556, 1.196, 0.000, 0.290},
{0.000, 0.888, 0.507, 18.231, 0.428, 0.456, 0.565, 0.524, 0.517, 0.587, 0.460, 0.650, 0.681, 0.601, 0.403, 0.481, 0.428, 0.830, 0.818, 0.809, 0.312, 0.750, 0.539, 0.466, 0.000, 0.290},
{0.000, 0.660, 4.021, 0.428, 6.112, 1.658, 0.337, 0.745, 0.884, 0.370, 0.890, 0.373, 0.435, 1.558, 0.710, 0.967, 0.678, 0.921, 0.825, 0.432, 0.307, 0.750, 0.504, 1.394, 0.000, 0.290},
{0.000, 0.797, 1.319, 0.456, 1.658, 4.437, 0.456, 0.540, 0.911, 0.416, 1.331, 0.478, 0.605, 0.920, 0.839, 1.671, 0.976, 0.882, 0.819, 0.479, 0.548, 0.750, 0.652, 3.380, 0.000, 0.290},
{0.000, 0.546, 0.384, 0.565, 0.337, 0.456, 6.636, 0.414, 0.755, 0.990, 0.445, 1.262, 1.052, 0.439, 0.376, 0.417, 0.462, 0.553, 0.570, 0.860, 1.348, 0.750, 2.424, 0.441, 0.000, 0.290},
{0.000, 1.101, 0.848, 0.524, 0.745, 0.540, 0.414, 5.792, 0.601, 0.370, 0.655, 0.377, 0.519, 0.969, 0.620, 0.641, 0.517, 0.999, 0.636, 0.403, 0.505, 0.750, 0.467, 0.579, 0.000, 0.290},
{0.000, 0.641, 1.118, 0.517, 0.884, 0.911, 0.755, 0.601, 10.449, 0.411, 0.946, 0.547, 0.760, 1.394, 0.582, 1.209, 0.982, 0.823, 0.653, 0.414, 0.475, 0.750, 1.570, 1.025, 0.000, 0.290},
{0.000, 0.715, 0.407, 0.587, 0.370, 0.416, 0.990, 0.370, 0.411, 3.411, 0.468, 1.697, 1.438, 0.451, 0.511, 0.503, 0.435, 0.546, 0.861, 2.313, 0.522, 0.750, 0.826, 0.449, 0.000, 0.290},
{0.000, 0.748, 0.968, 0.460, 0.890, 1.331, 0.445, 0.655, 0.946, 0.468, 3.881, 0.479, 0.685, 1.060, 0.764, 1.419, 2.065, 0.893, 0.845, 0.523, 0.462, 0.750, 0.668, 1.365, 0.000, 0.290},
{0.000, 0.657, 0.391, 0.650, 0.373, 0.478, 1.262, 0.377, 0.547, 1.697, 0.479, 3.328, 1.790, 0.413, 0.444, 0.563, 0.554, 0.511, 0.759, 1.324, 0.602, 0.750, 0.858, 0.511, 0.000, 0.290},
{0.000, 0.854, 0.516, 0.681, 0.435, 0.605, 1.052, 0.519, 0.760, 1.438, 0.685, 1.790, 4.816, 0.612, 0.545, 0.960, 0.678, 0.682, 0.882, 1.213, 0.761, 0.750, 0.918, 0.741, 0.000, 0.290},
{0.000, 0.720, 3.269, 0.601, 1.558, 0.920, 0.439, 0.969, 1.394, 0.451, 1.060, 0.413, 0.612, 5.285, 0.604, 1.035, 0.854, 1.224, 1.109, 0.463, 0.376, 0.750, 0.617, 0.964, 0.000, 0.290},
{0.000, 0.715, 0.661, 0.403, 0.710, 0.839, 0.376, 0.620, 0.582, 0.511, 0.764, 0.444, 0.545, 0.604, 10.204, 0.750, 0.519, 0.759, 0.749, 0.524, 0.420, 0.750, 0.468, 0.805, 0.000, 0.290},
{0.000, 0.820, 0.998, 0.481, 0.967, 1.671, 0.417, 0.641, 1.209, 0.503, 1.419, 0.563, 0.960, 1.035, 0.750, 4.697, 1.357, 1.069, 0.810, 0.557, 0.715, 0.750, 0.742, 2.828, 0.000, 0.290},
{0.000, 0.668, 0.759, 0.428, 0.678, 0.976, 0.462, 0.517, 0.982, 0.435, 2.065, 0.554, 0.678, 0.854, 0.519, 1.357, 5.378, 0.804, 0.737, 0.512, 0.529, 0.750, 0.727, 1.122, 0.000, 0.290},
{0.000, 1.364, 1.061, 0.830, 0.921, 0.882, 0.553, 0.999, 0.823, 0.546, 0.893, 0.511, 0.682, 1.224, 0.759, 1.069, 0.804, 3.143, 1.497, 0.679, 0.392, 0.750, 0.651, 0.953, 0.000, 0.290},
{0.000, 0.967, 0.955, 0.818, 0.825, 0.819, 0.570, 0.636, 0.653, 0.861, 0.845, 0.759, 0.882, 1.109, 0.749, 0.810, 0.737, 1.497, 3.553, 1.060, 0.503, 0.750, 0.691, 0.816, 0.000, 0.290},
{0.000, 0.982, 0.446, 0.809, 0.432, 0.479, 0.860, 0.403, 0.414, 2.313, 0.523, 1.324, 1.213, 0.463, 0.524, 0.557, 0.512, 0.679, 1.060, 3.118, 0.485, 0.750, 0.727, 0.509, 0.000, 0.290},
{0.000, 0.464, 0.339, 0.312, 0.307, 0.548, 1.348, 0.505, 0.475, 0.522, 0.462, 0.602, 0.761, 0.376, 0.420, 0.715, 0.529, 0.392, 0.503, 0.485, 31.361, 0.750, 1.765, 0.612, 0.000, 0.290},
{0.000, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.750, 0.000, 0.290},
{0.000, 0.596, 0.556, 0.539, 0.504, 0.652, 2.424, 0.467, 1.570, 0.826, 0.668, 0.858, 0.918, 0.617, 0.468, 0.742, 0.727, 0.651, 0.691, 0.727, 1.765, 0.750, 6.893, 0.686, 0.000, 0.290},
{0.000, 0.806, 1.196, 0.466, 1.394, 3.380, 0.441, 0.579, 1.025, 0.449, 1.365, 0.511, 0.741, 0.964, 0.805, 2.828, 1.122, 0.953, 0.816, 0.509, 0.612, 0.750, 0.686, 3.169, 0.000, 0.290},
{0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.290},
{0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 0.290, 1.333},
};

static const double BLOSUM90_FREQRATIOS[BLASTAA_SIZE][BLASTAA_SIZE] = {
{0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.120},
{0.000, 4.773, 0.477, 0.732, 0.451, 0.703, 0.397, 0.957, 0.514, 0.543, 0.723, 0.505, 0.625, 0.510, 0.771, 0.696, 0.555, 1.535, 0.980, 0.866, 0.309, 0.707, 0.436, 0.700, 0.000, 0.120},
{0.000, 0.477, 5.362, 0.252, 5.759, 1.269, 0.252, 0.639, 0.830, 0.234, 0.793, 0.221, 0.310, 4.868, 0.428, 0.850, 0.609, 0.948, 0.743, 0.268, 0.179, 0.707, 0.307, 1.109, 0.000, 0.120},
{0.000, 0.732, 0.252, 20.702, 0.214, 0.180, 0.395, 0.272, 0.221, 0.581, 0.241, 0.493, 0.499, 0.300, 0.269, 0.295, 0.233, 0.576, 0.602, 0.634, 0.302, 0.707, 0.308, 0.224, 0.000, 0.120},
{0.000, 0.451, 5.759, 0.214, 9.106, 1.635, 0.234, 0.541, 0.594, 0.214, 0.677, 0.197, 0.252, 1.584, 0.452, 0.763, 0.477, 0.774, 0.611, 0.245, 0.145, 0.707, 0.245, 1.303, 0.000, 0.120},
{0.000, 0.703, 1.269, 0.180, 1.635, 6.995, 0.249, 0.399, 0.901, 0.264, 1.195, 0.276, 0.429, 0.811, 0.581, 1.906, 0.832, 0.845, 0.685, 0.369, 0.241, 0.707, 0.333, 5.054, 0.000, 0.120},
{0.000, 0.397, 0.252, 0.395, 0.234, 0.249, 9.486, 0.249, 0.572, 0.841, 0.283, 1.114, 0.893, 0.273, 0.237, 0.285, 0.287, 0.369, 0.445, 0.649, 1.089, 0.707, 2.780, 0.263, 0.000, 0.120},
{0.000, 0.957, 0.639, 0.272, 0.541, 0.399, 0.249, 7.882, 0.387, 0.184, 0.483, 0.210, 0.286, 0.761, 0.347, 0.425, 0.377, 0.784, 0.492, 0.251, 0.264, 0.707, 0.230, 0.409, 0.000, 0.120},
{0.000, 0.514, 0.830, 0.221, 0.594, 0.901, 0.572, 0.387, 16.070, 0.258, 0.740, 0.314, 0.432, 1.124, 0.420, 1.316, 0.925, 0.661, 0.540, 0.289, 0.390, 0.707, 1.819, 1.059, 0.000, 0.120},
{0.000, 0.543, 0.234, 0.581, 0.214, 0.264, 0.841, 0.184, 0.258, 4.868, 0.313, 1.665, 1.512, 0.258, 0.286, 0.309, 0.299, 0.379, 0.701, 2.496, 0.343, 0.707, 0.539, 0.281, 0.000, 0.120},
{0.000, 0.723, 0.793, 0.241, 0.677, 1.195, 0.283, 0.483, 0.740, 0.313, 6.326, 0.357, 0.534, 0.938, 0.597, 1.524, 2.192, 0.820, 0.736, 0.370, 0.241, 0.707, 0.408, 1.320, 0.000, 0.120},
{0.000, 0.505, 0.221, 0.493, 0.197, 0.276, 1.114, 0.210, 0.314, 1.665, 0.357, 4.463, 2.123, 0.250, 0.303, 0.407, 0.363, 0.368, 0.561, 1.220, 0.439, 0.707, 0.581, 0.326, 0.000, 0.120},
{0.000, 0.625, 0.310, 0.499, 0.252, 0.429, 0.893, 0.286, 0.432, 1.512, 0.534, 2.123, 8.883, 0.382, 0.362, 0.887, 0.506, 0.498, 0.758, 1.224, 0.561, 0.707, 0.550, 0.603, 0.000, 0.120},
{0.000, 0.510, 4.868, 0.300, 1.584, 0.811, 0.273, 0.761, 1.124, 0.258, 0.938, 0.250, 0.382, 8.963, 0.398, 0.958, 0.773, 1.165, 0.908, 0.297, 0.221, 0.707, 0.385, 0.867, 0.000, 0.120},
{0.000, 0.771, 0.428, 0.269, 0.452, 0.581, 0.237, 0.347, 0.420, 0.286, 0.597, 0.303, 0.362, 0.398, 15.155, 0.538, 0.446, 0.652, 0.560, 0.370, 0.178, 0.707, 0.258, 0.565, 0.000, 0.120},
{0.000, 0.696, 0.850, 0.295, 0.763, 1.906, 0.285, 0.425, 1.316, 0.309, 1.524, 0.407, 0.887, 0.958, 0.538, 8.340, 1.394, 0.859, 0.724, 0.411, 0.408, 0.707, 0.462, 4.360, 0.000, 0.120},
{0.000, 0.555, 0.609, 0.233, 0.477, 0.832, 0.287, 0.377, 0.925, 0.299, 2.192, 0.363, 0.506, 0.773, 0.446, 1.394, 8.245, 0.695, 0.598, 0.354, 0.294, 0.707, 0.418, 1.046, 0.000, 0.120},
{0.000, 1.535, 0.948, 0.576, 0.774, 0.845, 0.369, 0.784, 0.661, 0.379, 0.820, 0.368, 0.498, 1.165, 0.652, 0.859, 0.695, 5.106, 1.663, 0.494, 0.271, 0.707, 0.462, 0.850, 0.000, 0.120},
{0.000, 0.980, 0.743, 0.602, 0.611, 0.685, 0.445, 0.492, 0.540, 0.701, 0.736, 0.561, 0.758, 0.908, 0.560, 0.724, 0.598, 1.663, 6.205, 0.891, 0.285, 0.707, 0.474, 0.700, 0.000, 0.120},
{0.000, 0.866, 0.268, 0.634, 0.245, 0.369, 0.649, 0.251, 0.289, 2.496, 0.370, 1.220, 1.224, 0.297, 0.370, 0.411, 0.354, 0.494, 0.891, 4.584, 0.342, 0.707, 0.489, 0.385, 0.000, 0.120},
{0.000, 0.309, 0.179, 0.302, 0.145, 0.241, 1.089, 0.264, 0.390, 0.343, 0.241, 0.439, 0.561, 0.221, 0.178, 0.408, 0.294, 0.271, 0.285, 0.342, 41.552, 0.707, 2.036, 0.304, 0.000, 0.120},
{0.000, 0.707, 0.707, 0.707, 0.707, 0.707, 0.707, 0.707, 0.707, 0.707, 0.707, 0.707, 0.707, 0.707, 0.707, 0.707, 0.707, 0.707, 0.707, 0.707, 0.707, 0.707, 0.707, 0.707, 0.000, 0.120},
{0.000, 0.436, 0.307, 0.308, 0.245, 0.333, 2.780, 0.230, 1.819, 0.539, 0.408, 0.581, 0.550, 0.385, 0.258, 0.462, 0.418, 0.462, 0.474, 0.489, 2.036, 0.707, 12.194, 0.382, 0.000, 0.120},
{0.000, 0.700, 1.109, 0.224, 1.303, 5.054, 0.263, 0.409, 1.059, 0.281, 1.320, 0.326, 0.603, 0.867, 0.565, 4.360, 1.046, 0.850, 0.700, 0.385, 0.304, 0.707, 0.382, 4.789, 0.000, 0.120},
{0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.120},
{0.120, 0.120, 0.120, 0.120, 0.120, 0.120, 0.120, 0.120, 0.120, 0.120, 0.120, 0.120, 0.120, 0.120, 0.120, 0.120, 0.120, 0.120, 0.120, 0.120, 0.120, 0.120, 0.120, 0.120, 0.120, 1.333},
};

static const double PAM250_FREQRATIOS[BLASTAA_SIZE][BLASTAA_SIZE] = {
{0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.000, 0.170},
{0.000, 1.516, 1.056, 0.627, 1.070, 1.075, 0.446, 1.339, 0.732, 0.889, 0.766, 0.646, 0.770, 1.040, 1.294, 0.903, 0.701, 1.290, 1.317, 1.045, 0.264, 0.750, 0.450, 1.000, 0.000, 0.170},
{0.000, 1.056, 1.843, 0.365, 2.052, 1.825, 0.354, 1.119, 1.297, 0.617, 1.130, 0.453, 0.605, 1.600, 0.846, 1.339, 0.862, 1.117, 1.032, 0.638, 0.297, 0.750, 0.486, 1.613, 0.000, 0.170},
{0.000, 0.627, 0.365, 15.630, 0.307, 0.295, 0.371, 0.459, 0.452, 0.588, 0.286, 0.248, 0.299, 0.433, 0.527, 0.289, 0.430, 0.990, 0.601, 0.639, 0.169, 0.750, 1.078, 0.293, 0.000, 0.170},
{0.000, 1.070, 2.052, 0.307, 2.433, 2.197, 0.274, 1.147, 1.173, 0.580, 1.020, 0.398, 0.548, 1.610, 0.806, 1.461, 0.743, 1.069, 0.968, 0.612, 0.213, 0.750, 0.369, 1.877, 0.000, 0.170},